| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCP1A | DCP1B | ENSPPYP00000015428 | ENSPPYP00000004723 | DCP1A isoform 1. | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | 0.998 |
| DCP1A | DCP2 | ENSPPYP00000015428 | ENSPPYP00000018067 | DCP1A isoform 1. | m7GpppN-mRNA hydrolase; Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication- dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety. The presence of a N(6)-methyladenosine methylation at the second transcr [...] | 0.980 |
| DCP1A | DDX6 | ENSPPYP00000015428 | ENSPPYP00000004516 | DCP1A isoform 1. | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, may play a role in mRNA decapping. | 0.997 |
| DCP1A | EDC3 | ENSPPYP00000015428 | ENSPPYP00000007534 | DCP1A isoform 1. | Enhancer of mRNA-decapping protein 3; Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity); Belongs to the EDC3 family. | 0.997 |
| DCP1A | EDC4 | ENSPPYP00000015428 | ENSPPYP00000008440 | DCP1A isoform 1. | Enhancer of mRNA decapping 4. | 0.998 |
| DCP1A | ENSPPYP00000017543 | ENSPPYP00000015428 | ENSPPYP00000017543 | DCP1A isoform 1. | annotation not available | 0.994 |
| DCP1A | KIFBP | ENSPPYP00000015428 | ENSPPYP00000002772 | DCP1A isoform 1. | KIF1 binding protein. | 0.772 |
| DCP1A | LSM14A | ENSPPYP00000015428 | ENSPPYP00000011009 | DCP1A isoform 1. | Protein LSM14 homolog A; Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs. Belongs to the LSM14 family. | 0.819 |
| DCP1A | LSM4 | ENSPPYP00000015428 | ENSPPYP00000010908 | DCP1A isoform 1. | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.837 |
| DCP1A | XRN1 | ENSPPYP00000015428 | ENSPPYP00000015851 | DCP1A isoform 1. | 5'-3' exoribonuclease 1. | 0.993 |
| DCP1B | DCP1A | ENSPPYP00000004723 | ENSPPYP00000015428 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | DCP1A isoform 1. | 0.998 |
| DCP1B | DCP2 | ENSPPYP00000004723 | ENSPPYP00000018067 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | m7GpppN-mRNA hydrolase; Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication- dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety. The presence of a N(6)-methyladenosine methylation at the second transcr [...] | 0.953 |
| DCP1B | DDX6 | ENSPPYP00000004723 | ENSPPYP00000004516 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, may play a role in mRNA decapping. | 0.991 |
| DCP1B | EDC3 | ENSPPYP00000004723 | ENSPPYP00000007534 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | Enhancer of mRNA-decapping protein 3; Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity); Belongs to the EDC3 family. | 0.991 |
| DCP1B | EDC4 | ENSPPYP00000004723 | ENSPPYP00000008440 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | Enhancer of mRNA decapping 4. | 0.985 |
| DCP1B | ENSPPYP00000017543 | ENSPPYP00000004723 | ENSPPYP00000017543 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | annotation not available | 0.985 |
| DCP1B | KIFBP | ENSPPYP00000004723 | ENSPPYP00000002772 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | KIF1 binding protein. | 0.772 |
| DCP1B | LSM14A | ENSPPYP00000004723 | ENSPPYP00000011009 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | Protein LSM14 homolog A; Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs. Belongs to the LSM14 family. | 0.792 |
| DCP1B | LSM4 | ENSPPYP00000004723 | ENSPPYP00000010908 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.825 |
| DCP1B | XRN1 | ENSPPYP00000004723 | ENSPPYP00000015851 | mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity). | 5'-3' exoribonuclease 1. | 0.917 |
