STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCND2CCND2 isoform 1; Belongs to the cyclin family. (289 aa)    
Predicted Functional Partners:
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.999
CDK4
CDK4 isoform 2; Belongs to the protein kinase superfamily.
   
 0.999
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.999
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.999
RBL2
RBL2 isoform 2.
    
 0.992
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.991
RB1
RB1 isoform 1.
    
 0.985
CDKN1C
CDKN1C isoform 4.
   
 0.971
CDKN2C
Cyclin dependent kinase inhibitor 2C.
    
 0.969
RBL1
RBL1 isoform 1.
    
 0.968
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.