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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EMP1Epithelial membrane protein 1. (161 aa)    
Predicted Functional Partners:
WRN
WRN isoform 1.
      
 0.674
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.
      
 0.670
FGF23
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.579
SCARB1
SCARB1 isoform 7; Belongs to the CD36 family.
      
 0.503
PHEX
Phosphate regulating endopeptidase homolog X-linked.
      
 0.503
SCARB2
SCARB2 isoform 16; Belongs to the CD36 family.
      
 0.502
CD36
CD36 isoform 15; Belongs to the CD36 family.
      
 0.502
SLC34A1
SLC34A1 isoform 3.
      
 0.499
CR201_G0049742
SLC34A3 isoform 1.
      
 0.469
MYO1A
MYO1A isoform 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.457
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.