STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA5PLEKHA5 isoform 2. (1151 aa)    
Predicted Functional Partners:
FRMD4B
FRMD4B isoform 1.
    
 
 0.593
ITSN2
ITSN2 isoform 3.
   
  0.538
LATS2
Non-specific serine/threonine protein kinase.
    
 0.522
LATS1
Large tumor suppressor kinase 1.
    
 0.522
PDZD11
PDZ domain containing 11.
    
 0.480
PSMD4
PSMD4 isoform 1.
    
 0.476
BIRC6
BIRC6 isoform 1.
    
 0.448
TEAD4
TEAD4 isoform 4.
    
 0.446
TEAD2
TEA domain transcription factor 2.
    
 0.446
TEAD3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
    
 0.446
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.