SLCO1C1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1A2	CALB2	ENSPPYP00000000749	ENSPPYP00000023738	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	CALB2 isoform 1.	0.633
ATP1A2	DOP1B	ENSPPYP00000000749	ENSPPYP00000012726	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	DOP1 leucine zipper like protein B.	0.429
ATP1A2	LIX1	ENSPPYP00000000749	ENSPPYP00000017503	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Limb and CNS expressed 1.	0.675
ATP1A2	MOXD1	ENSPPYP00000000749	ENSPPYP00000019050	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Monooxygenase DBH like 1.	0.668
ATP1A2	S1PR1	ENSPPYP00000000749	ENSPPYP00000001284	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.574
ATP1A2	SCGN	ENSPPYP00000000749	ENSPPYP00000018218	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Secretagogin, EF-hand calcium binding protein.	0.690
ATP1A2	SLCO1C1	ENSPPYP00000000749	ENSPPYP00000004965	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Solute carrier organic anion transporter family member.	0.703
CALB2	ATP1A2	ENSPPYP00000023738	ENSPPYP00000000749	CALB2 isoform 1.	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	0.633
CALB2	LIX1	ENSPPYP00000023738	ENSPPYP00000017503	CALB2 isoform 1.	Limb and CNS expressed 1.	0.669
CALB2	MOXD1	ENSPPYP00000023738	ENSPPYP00000019050	CALB2 isoform 1.	Monooxygenase DBH like 1.	0.662
CALB2	S1PR1	ENSPPYP00000023738	ENSPPYP00000001284	CALB2 isoform 1.	S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.579
CALB2	SLCO1C1	ENSPPYP00000023738	ENSPPYP00000004965	CALB2 isoform 1.	Solute carrier organic anion transporter family member.	0.730
DOP1B	ATP1A2	ENSPPYP00000012726	ENSPPYP00000000749	DOP1 leucine zipper like protein B.	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	0.429
DOP1B	SLCO1C1	ENSPPYP00000012726	ENSPPYP00000004965	DOP1 leucine zipper like protein B.	Solute carrier organic anion transporter family member.	0.627
GPM6A	SLCO1C1	ENSPPYP00000016996	ENSPPYP00000004965	Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and re [...]	Solute carrier organic anion transporter family member.	0.590
LIX1	ATP1A2	ENSPPYP00000017503	ENSPPYP00000000749	Limb and CNS expressed 1.	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	0.675
LIX1	CALB2	ENSPPYP00000017503	ENSPPYP00000023738	Limb and CNS expressed 1.	CALB2 isoform 1.	0.669
LIX1	MOXD1	ENSPPYP00000017503	ENSPPYP00000019050	Limb and CNS expressed 1.	Monooxygenase DBH like 1.	0.777
LIX1	S1PR1	ENSPPYP00000017503	ENSPPYP00000001284	Limb and CNS expressed 1.	S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.629
LIX1	SCGN	ENSPPYP00000017503	ENSPPYP00000018218	Limb and CNS expressed 1.	Secretagogin, EF-hand calcium binding protein.	0.694