| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IKBKG | IRAK1 | ENSPPYP00000023381 | ENSPPYP00000023353 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Interleukin 1 receptor associated kinase 1. | 0.973 |
| IKBKG | IRAK2 | ENSPPYP00000023381 | ENSPPYP00000015274 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Interleukin-1 receptor-associated kinase-like 2; Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. | 0.858 |
| IKBKG | IRAK4 | ENSPPYP00000023381 | ENSPPYP00000005053 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | IRAK4 isoform 6. | 0.996 |
| IKBKG | MYD88 | ENSPPYP00000023381 | ENSPPYP00000015673 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.961 |
| IKBKG | PELI1 | ENSPPYP00000023381 | ENSPPYP00000013792 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. | 0.563 |
| IKBKG | TAB2 | ENSPPYP00000023381 | ENSPPYP00000019131 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.997 |
| IKBKG | TLR4 | ENSPPYP00000023381 | ENSPPYP00000021908 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | TLR4 isoform 1; Belongs to the Toll-like receptor family. | 0.908 |
| IKBKG | TLR8 | ENSPPYP00000023381 | ENSPPYP00000022512 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | TLR8 isoform 1; Belongs to the Toll-like receptor family. | 0.415 |
| IKBKG | TRAF6 | ENSPPYP00000023381 | ENSPPYP00000003845 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.998 |
| IRAK1 | IKBKG | ENSPPYP00000023353 | ENSPPYP00000023381 | Interleukin 1 receptor associated kinase 1. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.973 |
| IRAK1 | IRAK2 | ENSPPYP00000023353 | ENSPPYP00000015274 | Interleukin 1 receptor associated kinase 1. | Interleukin-1 receptor-associated kinase-like 2; Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. | 0.991 |
| IRAK1 | IRAK4 | ENSPPYP00000023353 | ENSPPYP00000005053 | Interleukin 1 receptor associated kinase 1. | IRAK4 isoform 6. | 0.999 |
| IRAK1 | MYD88 | ENSPPYP00000023353 | ENSPPYP00000015673 | Interleukin 1 receptor associated kinase 1. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.999 |
| IRAK1 | PELI1 | ENSPPYP00000023353 | ENSPPYP00000013792 | Interleukin 1 receptor associated kinase 1. | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. | 0.980 |
| IRAK1 | TAB2 | ENSPPYP00000023353 | ENSPPYP00000019131 | Interleukin 1 receptor associated kinase 1. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.997 |
| IRAK1 | TIRAP | ENSPPYP00000023353 | ENSPPYP00000004627 | Interleukin 1 receptor associated kinase 1. | TIR domain containing adaptor protein. | 0.977 |
| IRAK1 | TLR4 | ENSPPYP00000023353 | ENSPPYP00000021908 | Interleukin 1 receptor associated kinase 1. | TLR4 isoform 1; Belongs to the Toll-like receptor family. | 0.777 |
| IRAK1 | TLR8 | ENSPPYP00000023353 | ENSPPYP00000022512 | Interleukin 1 receptor associated kinase 1. | TLR8 isoform 1; Belongs to the Toll-like receptor family. | 0.969 |
| IRAK1 | TRAF6 | ENSPPYP00000023353 | ENSPPYP00000003845 | Interleukin 1 receptor associated kinase 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.999 |
| IRAK2 | IKBKG | ENSPPYP00000015274 | ENSPPYP00000023381 | Interleukin-1 receptor-associated kinase-like 2; Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.858 |
