| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP1B1 | AP1G1 | ENSPPYP00000013038 | ENSPPYP00000008496 | AP complex subunit beta. | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | 0.999 |
| AP1B1 | AP4B1 | ENSPPYP00000013038 | ENSPPYP00000001174 | AP complex subunit beta. | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | 0.617 |
| AP1B1 | AP4E1 | ENSPPYP00000013038 | ENSPPYP00000007336 | AP complex subunit beta. | AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. | 0.861 |
| AP1B1 | AP4M1 | ENSPPYP00000013038 | ENSPPYP00000019498 | AP complex subunit beta. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.879 |
| AP1B1 | ARF3 | ENSPPYP00000013038 | ENSPPYP00000005106 | AP complex subunit beta. | ADP-ribosylation factor 3; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | 0.818 |
| AP1B1 | ITSN2 | ENSPPYP00000013038 | ENSPPYP00000014069 | AP complex subunit beta. | ITSN2 isoform 3. | 0.986 |
| AP1G1 | AP1B1 | ENSPPYP00000008496 | ENSPPYP00000013038 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | AP complex subunit beta. | 0.999 |
| AP1G1 | AP4B1 | ENSPPYP00000008496 | ENSPPYP00000001174 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | 0.881 |
| AP1G1 | AP4E1 | ENSPPYP00000008496 | ENSPPYP00000007336 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. | 0.617 |
| AP1G1 | AP4M1 | ENSPPYP00000008496 | ENSPPYP00000019498 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.878 |
| AP1G1 | ARF3 | ENSPPYP00000008496 | ENSPPYP00000005106 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | ADP-ribosylation factor 3; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | 0.733 |
| AP1G1 | COPB1 | ENSPPYP00000008496 | ENSPPYP00000003980 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | 0.522 |
| AP1G1 | ITSN2 | ENSPPYP00000008496 | ENSPPYP00000014069 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | ITSN2 isoform 3. | 0.925 |
| AP4B1 | AP1B1 | ENSPPYP00000001174 | ENSPPYP00000013038 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | AP complex subunit beta. | 0.617 |
| AP4B1 | AP1G1 | ENSPPYP00000001174 | ENSPPYP00000008496 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | 0.881 |
| AP4B1 | AP4E1 | ENSPPYP00000001174 | ENSPPYP00000007336 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. | 0.999 |
| AP4B1 | AP4M1 | ENSPPYP00000001174 | ENSPPYP00000019498 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.999 |
| AP4B1 | ARF3 | ENSPPYP00000001174 | ENSPPYP00000005106 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | ADP-ribosylation factor 3; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | 0.765 |
| AP4B1 | ITSN2 | ENSPPYP00000001174 | ENSPPYP00000014069 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. | ITSN2 isoform 3. | 0.986 |
| AP4E1 | AP1B1 | ENSPPYP00000007336 | ENSPPYP00000013038 | AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. | AP complex subunit beta. | 0.861 |
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