STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)    
Predicted Functional Partners:
BOC
BOC isoform 3.
    
 0.994
PTCH2
PTCH2 isoform 1.
   
 0.993
HHIP
HHIP isoform 1.
    
 0.987
PTCH1
PTCH1 isoform 7.
   
 0.971
GAS1
Growth arrest specific 1.
    
 0.966
CDON
CDON isoform 2.
    
 0.962
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
  
  
0.952
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
  
  
0.951
LRP2
LRP2 isoform 1.
     
 0.909
DISP1
Dispatched RND transporter family member 1.
   
 0.839
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.