LARP4 protein (Pongo abelii) - STRING interaction network

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[Homology]

Score

LARP4

LARP4 isoform 3. (521 aa)

Predicted Functional Partners:

CR201_G0044109-2

0.752

PABPC1

0.676

PABPC3

0.667

RACK1

0.648

FLNA

0.626

G3BP1

0.569

LARP4B

0.565

CR201_G0044109

0.564

ENSPPYP00000014325

0.538

SYNCRIP

0.538

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0044109	G3BP1	ENSPPYP00000002420	ENSPPYP00000017869	RACK1 isoform 5.	Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...]	0.531
CR201_G0044109	LARP4	ENSPPYP00000002420	ENSPPYP00000005151	RACK1 isoform 5.	LARP4 isoform 3.	0.564
CR201_G0044109	LARP4B	ENSPPYP00000002420	ENSPPYP00000002354	RACK1 isoform 5.	LARP4B isoform 2.	0.747
CR201_G0044109	RACK1	ENSPPYP00000002420	ENSPPYP00000022328	RACK1 isoform 5.	RACK1 isoform 13.	0.900
CR201_G0044109-2	ENSPPYP00000014325	ENSPPYP00000024445	ENSPPYP00000014325	RACK1 isoform 22.	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	0.493
CR201_G0044109-2	G3BP1	ENSPPYP00000024445	ENSPPYP00000017869	RACK1 isoform 22.	Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...]	0.531
CR201_G0044109-2	LARP4	ENSPPYP00000024445	ENSPPYP00000005151	RACK1 isoform 22.	LARP4 isoform 3.	0.752
CR201_G0044109-2	LARP4B	ENSPPYP00000024445	ENSPPYP00000002354	RACK1 isoform 22.	LARP4B isoform 2.	0.773
CR201_G0044109-2	PABPC1	ENSPPYP00000024445	ENSPPYP00000021076	RACK1 isoform 22.	Polyadenylate-binding protein 1; Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region deter [...]	0.643
CR201_G0044109-2	SYNCRIP	ENSPPYP00000024445	ENSPPYP00000018830	RACK1 isoform 22.	Synaptotagmin binding cytoplasmic RNA interacting protein.	0.434
ENSPPYP00000014325	CR201_G0044109-2	ENSPPYP00000014325	ENSPPYP00000024445	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	RACK1 isoform 22.	0.493
ENSPPYP00000014325	G3BP1	ENSPPYP00000014325	ENSPPYP00000017869	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...]	0.845
ENSPPYP00000014325	LARP4	ENSPPYP00000014325	ENSPPYP00000005151	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	LARP4 isoform 3.	0.538
ENSPPYP00000014325	LARP4B	ENSPPYP00000014325	ENSPPYP00000002354	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	LARP4B isoform 2.	0.676
ENSPPYP00000014325	PABPC3	ENSPPYP00000014325	ENSPPYP00000005945	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.963
ENSPPYP00000014325	RACK1	ENSPPYP00000014325	ENSPPYP00000022328	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	RACK1 isoform 13.	0.493
ENSPPYP00000014325	SYNCRIP	ENSPPYP00000014325	ENSPPYP00000018830	LOW QUALITY PROTEIN: polyadenylate-binding protein 1.	Synaptotagmin binding cytoplasmic RNA interacting protein.	0.671
FLNA	LARP4	ENSPPYP00000023360	ENSPPYP00000005151	FLNA isoform 7.	LARP4 isoform 3.	0.626
G3BP1	CR201_G0044109	ENSPPYP00000017869	ENSPPYP00000002420	Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...]	RACK1 isoform 5.	0.531
G3BP1	CR201_G0044109-2	ENSPPYP00000017869	ENSPPYP00000024445	Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...]	RACK1 isoform 22.	0.531