Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MUCL1MUCL1 isoform 4. (90 aa)    
Predicted Functional Partners:
EMC4
ER membrane protein complex subunit 4; May mediate anti-apoptotic activity.
    
   0.738
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
   
   0.634
MMGT1
Membrane magnesium transporter 1; Mediates Mg(2+) transport.
    
   0.634
SCGB2A2
SCGB2A2 isoform 1.
   
  
 0.622
SCGB2A2-2
Secretoglobin family 2A member 2.
   
  
 0.622
EMC1
ER membrane protein complex subunit 1; Belongs to the EMC1 family.
   
   0.589
CDC73
Cell division cycle 73.
   
 0.515
PAF1
RNA polymerase II-associated factor 1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser- 5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription [...]
   
 0.478
FANCA
FANCA isoform 6.
     
 0.466
CTR9
CTR9 isoform 1.
   
 0.462
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.