Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PMELPMEL isoform 9. (574 aa)    
Predicted Functional Partners:
WDR46
WD repeat domain 46.
   
 0.954
NOP14
NOP14 nucleolar protein.
   
 0.947
UTP18
UTP18 isoform 2.
   
 0.940
UTP15
U3 small nucleolar RNA-associated protein 15 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA.
   
 0.940
UTP4
UTP4 small subunit processome component.
   
  0.939
PDCD11
PDCD11 isoform 1.
   
 0.938
DCAF13
DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family.
   
 0.937
UTP14A
UTP14A isoform 2.
   
 0.937
WDR36
WD repeat domain 36.
   
 
 0.930
WDR75
WD repeat domain 75.
   
 0.926
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.