STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB5BRas-related protein Rab-5B; Protein transport. Probably involved in vesicular traffic (By similarity). (285 aa)    
Predicted Functional Partners:
RAB5A
RAB5A, member RAS oncogene family.
  
 
0.998
RIN1
RIN1 isoform 2.
    
 0.954
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.954
RAB5C
Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.
  
 
0.944
RABGEF1
RABGEF1 isoform 2.
   
 0.919
LRRK2
LRRK2 isoform 3.
    
 
 0.832
APPL1
APPL1 isoform 1.
   
 
 0.803
APPL2
APPL2 isoform 1.
   
 
 0.802
NBR1
Next to BRCA1 gene 1 protein; Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
   
  
 0.769
RIN3
RIN3 isoform 1.
    
 0.765
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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