Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BIRC6 | NEDD4 | ENSPPYP00000013966 | ENSPPYP00000007372 | BIRC6 isoform 1. | E3 ubiquitin-protein ligase. | 0.448 |
BIRC6 | NEDD4L | ENSPPYP00000013966 | ENSPPYP00000010317 | BIRC6 isoform 1. | E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF- beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, KCNH2, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiq [...] | 0.448 |
BIRC6 | RNF41 | ENSPPYP00000013966 | ENSPPYP00000005297 | BIRC6 isoform 1. | E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus. Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hematopoietic progeni [...] | 0.934 |
BIRC6 | SMURF2 | ENSPPYP00000013966 | ENSPPYP00000009604 | BIRC6 isoform 1. | E3 ubiquitin-protein ligase. | 0.448 |
BIRC6 | TRAF6 | ENSPPYP00000013966 | ENSPPYP00000003845 | BIRC6 isoform 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.698 |
BIRC6 | USP8 | ENSPPYP00000013966 | ENSPPYP00000007332 | BIRC6 isoform 1. | USP8 isoform 3; Belongs to the peptidase C19 family. | 0.770 |
CBL | CBLB | ENSPPYP00000004540 | ENSPPYP00000015183 | Cbl proto-oncogene. | Cbl proto-oncogene B. | 0.920 |
CBL | ERBB3 | ENSPPYP00000004540 | ENSPPYP00000005288 | Cbl proto-oncogene. | Receptor tyrosine-protein kinase erbB-3; Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. | 0.716 |
CBL | MDM2 | ENSPPYP00000004540 | ENSPPYP00000005415 | Cbl proto-oncogene. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.914 |
CBL | NEDD4 | ENSPPYP00000004540 | ENSPPYP00000007372 | Cbl proto-oncogene. | E3 ubiquitin-protein ligase. | 0.957 |
CBL | NEDD4L | ENSPPYP00000004540 | ENSPPYP00000010317 | Cbl proto-oncogene. | E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF- beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, KCNH2, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiq [...] | 0.927 |
CBL | RNF41 | ENSPPYP00000004540 | ENSPPYP00000005297 | Cbl proto-oncogene. | E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus. Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hematopoietic progeni [...] | 0.918 |
CBL | SMURF2 | ENSPPYP00000004540 | ENSPPYP00000009604 | Cbl proto-oncogene. | E3 ubiquitin-protein ligase. | 0.921 |
CBL | TRAF6 | ENSPPYP00000004540 | ENSPPYP00000003845 | Cbl proto-oncogene. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.970 |
CBLB | CBL | ENSPPYP00000015183 | ENSPPYP00000004540 | Cbl proto-oncogene B. | Cbl proto-oncogene. | 0.920 |
CBLB | ERBB3 | ENSPPYP00000015183 | ENSPPYP00000005288 | Cbl proto-oncogene B. | Receptor tyrosine-protein kinase erbB-3; Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. | 0.709 |
CBLB | MDM2 | ENSPPYP00000015183 | ENSPPYP00000005415 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.910 |
CBLB | NEDD4 | ENSPPYP00000015183 | ENSPPYP00000007372 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase. | 0.927 |
CBLB | NEDD4L | ENSPPYP00000015183 | ENSPPYP00000010317 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF- beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, KCNH2, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiq [...] | 0.917 |
CBLB | RNF41 | ENSPPYP00000015183 | ENSPPYP00000005297 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase NRDP1; Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus. Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hematopoietic progeni [...] | 0.912 |
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