Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD52Ankyrin repeat domain 52. (1076 aa)    
Predicted Functional Partners:
PPP6C
Serine/threonine-protein phosphatase.
    
 0.941
PPP6R2
PPP6R2 isoform 5.
    
 0.937
PPP6R1
PPP6R1 isoform 1.
    
 0.860
PPP6R3
PPP6R3 isoform 7.
    
 0.798
FAM98A
Protein FAM98A; Positively stimulates PRMT1-induced protein arginine methylation. Involved in skeletal homeostasis. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts; Belongs to the FAM98 family.
      
 0.781
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.749
NICN1
Nicolin-1.
      
 0.689
AGBL5
ATP/GTP binding protein like 5.
    
 
 0.637
GGCT
GGCT isoform 1.
    
 
 0.600
ANKRD44
ANKRD44 isoform 8.
    
 0.562
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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