SPRYD4 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPRYD4

SPRY domain containing 4. (207 aa)

Predicted Functional Partners:

MIP

0.867

GLS2

0.866

LYZL4

0.792

YEATS4

0.773

CCNT1

0.732

LYZL6

0.720

CPM

0.659

TMEM192

0.636

C12orf71

0.616

NUP107

0.565

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12orf71	CPM	ENSPPYP00000004998	ENSPPYP00000005417	C12orf71 isoform 1.	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	0.590
C12orf71	GLS2	ENSPPYP00000004998	ENSPPYP00000005314	C12orf71 isoform 1.	GLS2 isoform 5.	0.616
C12orf71	LYZL4	ENSPPYP00000004998	ENSPPYP00000015639	C12orf71 isoform 1.	LYZL4 isoform 1; Belongs to the glycosyl hydrolase 22 family.	0.639
C12orf71	LYZL6	ENSPPYP00000004998	ENSPPYP00000009216	C12orf71 isoform 1.	Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.	0.591
C12orf71	MIP	ENSPPYP00000004998	ENSPPYP00000005312	C12orf71 isoform 1.	Major intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.616
C12orf71	NUP107	ENSPPYP00000004998	ENSPPYP00000005413	C12orf71 isoform 1.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.590
C12orf71	SPRYD4	ENSPPYP00000004998	ENSPPYP00000005313	C12orf71 isoform 1.	SPRY domain containing 4.	0.616
C12orf71	YEATS4	ENSPPYP00000004998	ENSPPYP00000005420	C12orf71 isoform 1.	YEATS domain containing 4.	0.768
CCNT1	GLS2	ENSPPYP00000005098	ENSPPYP00000005314	CCNT1 isoform 2; Belongs to the cyclin family.	GLS2 isoform 5.	0.647
CCNT1	LYZL4	ENSPPYP00000005098	ENSPPYP00000015639	CCNT1 isoform 2; Belongs to the cyclin family.	LYZL4 isoform 1; Belongs to the glycosyl hydrolase 22 family.	0.435
CCNT1	MIP	ENSPPYP00000005098	ENSPPYP00000005312	CCNT1 isoform 2; Belongs to the cyclin family.	Major intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.681
CCNT1	SPRYD4	ENSPPYP00000005098	ENSPPYP00000005313	CCNT1 isoform 2; Belongs to the cyclin family.	SPRY domain containing 4.	0.732
CCNT1	YEATS4	ENSPPYP00000005098	ENSPPYP00000005420	CCNT1 isoform 2; Belongs to the cyclin family.	YEATS domain containing 4.	0.504
CPM	C12orf71	ENSPPYP00000005417	ENSPPYP00000004998	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	C12orf71 isoform 1.	0.590
CPM	GLS2	ENSPPYP00000005417	ENSPPYP00000005314	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	GLS2 isoform 5.	0.534
CPM	LYZL4	ENSPPYP00000005417	ENSPPYP00000015639	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	LYZL4 isoform 1; Belongs to the glycosyl hydrolase 22 family.	0.668
CPM	LYZL6	ENSPPYP00000005417	ENSPPYP00000009216	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.	0.620
CPM	MIP	ENSPPYP00000005417	ENSPPYP00000005312	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	Major intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.592
CPM	NUP107	ENSPPYP00000005417	ENSPPYP00000005413	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.811
CPM	SPRYD4	ENSPPYP00000005417	ENSPPYP00000005313	Carboxypeptidase M; Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity); Belongs to the peptidase M14 family.	SPRY domain containing 4.	0.659