TBK1 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALCOCO2	IKBKE	ENSPPYP00000009996	ENSPPYP00000000308	Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen- containing autophagosome maturation (By similarity). Bacteria targeting [...]	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.749
CALCOCO2	IRF3	ENSPPYP00000009996	ENSPPYP00000011485	Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen- containing autophagosome maturation (By similarity). Bacteria targeting [...]	IRF3 isoform 6.	0.793
CALCOCO2	SQSTM1	ENSPPYP00000009996	ENSPPYP00000018045	Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen- containing autophagosome maturation (By similarity). Bacteria targeting [...]	Sequestosome-1; Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin- containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation (By similarity). May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and [...]	0.956
CALCOCO2	TBK1	ENSPPYP00000009996	ENSPPYP00000005386	Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen- containing autophagosome maturation (By similarity). Bacteria targeting [...]	TANK binding kinase 1.	0.994
EXOC2	IKBKE	ENSPPYP00000018079	ENSPPYP00000000308	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.666
EXOC2	TBK1	ENSPPYP00000018079	ENSPPYP00000005386	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	TANK binding kinase 1.	0.987
IKBKE	CALCOCO2	ENSPPYP00000000308	ENSPPYP00000009996	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen- containing autophagosome maturation (By similarity). Bacteria targeting [...]	0.749
IKBKE	EXOC2	ENSPPYP00000000308	ENSPPYP00000018079	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.666
IKBKE	IKBKG	ENSPPYP00000000308	ENSPPYP00000023381	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.982
IKBKE	IRF3	ENSPPYP00000000308	ENSPPYP00000011485	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	IRF3 isoform 6.	0.999
IKBKE	IRF7	ENSPPYP00000000308	ENSPPYP00000003337	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	IRF7 isoform 12.	0.987
IKBKE	SQSTM1	ENSPPYP00000000308	ENSPPYP00000018045	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Sequestosome-1; Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin- containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation (By similarity). May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and [...]	0.826
IKBKE	STING1	ENSPPYP00000000308	ENSPPYP00000017715	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Transmembrane protein 173.	0.995
IKBKE	TANK	ENSPPYP00000000308	ENSPPYP00000014373	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TANK isoform 2.	0.997
IKBKE	TBK1	ENSPPYP00000000308	ENSPPYP00000005386	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TANK binding kinase 1.	0.999
IKBKE	TRAF3	ENSPPYP00000000308	ENSPPYP00000007003	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.997
IKBKG	IKBKE	ENSPPYP00000023381	ENSPPYP00000000308	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.982
IKBKG	IRF3	ENSPPYP00000023381	ENSPPYP00000011485	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	IRF3 isoform 6.	0.942
IKBKG	IRF7	ENSPPYP00000023381	ENSPPYP00000003337	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	IRF7 isoform 12.	0.930
IKBKG	SQSTM1	ENSPPYP00000023381	ENSPPYP00000018045	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Sequestosome-1; Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin- containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation (By similarity). May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and [...]	0.767