| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BLOC1S1 | DNASE2 | ENSPPYP00000005273 | ENSPPYP00000010775 | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] | Deoxyribonuclease 2, lysosomal. | 0.564 |
| BLOC1S1 | DNASE2B | ENSPPYP00000005273 | ENSPPYP00000001397 | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] | Deoxyribonuclease 2 beta. | 0.564 |
| BLOC1S1 | GNS | ENSPPYP00000005273 | ENSPPYP00000005389 | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.690 |
| BLOC1S1 | M6PR | ENSPPYP00000005273 | ENSPPYP00000004844 | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] | Mannose-6-phosphate receptor, cation dependent. | 0.678 |
| DNASE2 | BLOC1S1 | ENSPPYP00000010775 | ENSPPYP00000005273 | Deoxyribonuclease 2, lysosomal. | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] | 0.564 |
| DNASE2 | DNASE2B | ENSPPYP00000010775 | ENSPPYP00000001397 | Deoxyribonuclease 2, lysosomal. | Deoxyribonuclease 2 beta. | 0.965 |
| DNASE2 | GNS | ENSPPYP00000010775 | ENSPPYP00000005389 | Deoxyribonuclease 2, lysosomal. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.674 |
| DNASE2 | M6PR | ENSPPYP00000010775 | ENSPPYP00000004844 | Deoxyribonuclease 2, lysosomal. | Mannose-6-phosphate receptor, cation dependent. | 0.530 |
| DNASE2B | BLOC1S1 | ENSPPYP00000001397 | ENSPPYP00000005273 | Deoxyribonuclease 2 beta. | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] | 0.564 |
| DNASE2B | DNASE2 | ENSPPYP00000001397 | ENSPPYP00000010775 | Deoxyribonuclease 2 beta. | Deoxyribonuclease 2, lysosomal. | 0.965 |
| DNASE2B | GNS | ENSPPYP00000001397 | ENSPPYP00000005389 | Deoxyribonuclease 2 beta. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.759 |
| DNASE2B | M6PR | ENSPPYP00000001397 | ENSPPYP00000004844 | Deoxyribonuclease 2 beta. | Mannose-6-phosphate receptor, cation dependent. | 0.530 |
| GLB1 | GNS | ENSPPYP00000015702 | ENSPPYP00000005389 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.937 |
| GLB1 | GUSB | ENSPPYP00000015702 | ENSPPYP00000019644 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | 0.479 |
| GLB1 | HEXA | ENSPPYP00000015702 | ENSPPYP00000007503 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.947 |
| GLB1 | HEXB | ENSPPYP00000015702 | ENSPPYP00000024213 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | Beta-hexosaminidase. | 0.942 |
| GNS | BLOC1S1 | ENSPPYP00000005389 | ENSPPYP00000005273 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] | 0.690 |
| GNS | DNASE2 | ENSPPYP00000005389 | ENSPPYP00000010775 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Deoxyribonuclease 2, lysosomal. | 0.674 |
| GNS | DNASE2B | ENSPPYP00000005389 | ENSPPYP00000001397 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Deoxyribonuclease 2 beta. | 0.759 |
| GNS | GLB1 | ENSPPYP00000005389 | ENSPPYP00000015702 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | 0.937 |
