MYF5 protein (Pongo abelii) - STRING interaction network

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MYF5

Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)

Predicted Functional Partners:

PAX7

0.789

PAX3

0.769

TCF12

0.766

MEF2C

0.756

EP300

0.754

MEF2A

0.737

ID1

0.727

TCF4

0.726

TCF3

0.710

CREBBP

0.696

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSPPYP00000007974	ENSPPYP00000013236	CREBBP isoform 1.	EP300 isoform 1.	0.999
CREBBP	MEF2A	ENSPPYP00000007974	ENSPPYP00000007730	CREBBP isoform 1.	Myocyte-specific enhancer factor 2A; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylate [...]	0.512
CREBBP	MEF2C	ENSPPYP00000007974	ENSPPYP00000017465	CREBBP isoform 1.	Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...]	0.710
CREBBP	MYF5	ENSPPYP00000007974	ENSPPYP00000005474	CREBBP isoform 1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.696
CREBBP	TCF12	ENSPPYP00000007974	ENSPPYP00000007376	CREBBP isoform 1.	TCF12 isoform 1.	0.798
CREBBP	TCF3	ENSPPYP00000007974	ENSPPYP00000010467	CREBBP isoform 1.	TCF3 isoform 5.	0.872
CREBBP	TCF4	ENSPPYP00000007974	ENSPPYP00000010306	CREBBP isoform 1.	TCF4 isoform 16.	0.798
EP300	CREBBP	ENSPPYP00000013236	ENSPPYP00000007974	EP300 isoform 1.	CREBBP isoform 1.	0.999
EP300	ID1	ENSPPYP00000013236	ENSPPYP00000012162	EP300 isoform 1.	Inhibitor of DNA binding 1, HLH protein.	0.443
EP300	MEF2A	ENSPPYP00000013236	ENSPPYP00000007730	EP300 isoform 1.	Myocyte-specific enhancer factor 2A; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylate [...]	0.843
EP300	MEF2C	ENSPPYP00000013236	ENSPPYP00000017465	EP300 isoform 1.	Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...]	0.792
EP300	MYF5	ENSPPYP00000013236	ENSPPYP00000005474	EP300 isoform 1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.754
EP300	TCF12	ENSPPYP00000013236	ENSPPYP00000007376	EP300 isoform 1.	TCF12 isoform 1.	0.767
EP300	TCF3	ENSPPYP00000013236	ENSPPYP00000010467	EP300 isoform 1.	TCF3 isoform 5.	0.856
EP300	TCF4	ENSPPYP00000013236	ENSPPYP00000010306	EP300 isoform 1.	TCF4 isoform 16.	0.669
ID1	EP300	ENSPPYP00000012162	ENSPPYP00000013236	Inhibitor of DNA binding 1, HLH protein.	EP300 isoform 1.	0.443
ID1	MYF5	ENSPPYP00000012162	ENSPPYP00000005474	Inhibitor of DNA binding 1, HLH protein.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.727
ID1	TCF12	ENSPPYP00000012162	ENSPPYP00000007376	Inhibitor of DNA binding 1, HLH protein.	TCF12 isoform 1.	0.867
ID1	TCF3	ENSPPYP00000012162	ENSPPYP00000010467	Inhibitor of DNA binding 1, HLH protein.	TCF3 isoform 5.	0.952
ID1	TCF4	ENSPPYP00000012162	ENSPPYP00000010306	Inhibitor of DNA binding 1, HLH protein.	TCF4 isoform 16.	0.884

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