Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPFIA2PPFIA2 isoform 3. (1238 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 0.812
CASK
CASK isoform 2; Belongs to the MAGUK family.
    
 0.706
PPFIA3
PPFIA3 isoform 1.
   
  0.632
PTPRD
PTPRD isoform 1.
   
 0.590
ERC2
ERC2 isoform 1.
   
 
 0.583
PTPRF
PTPRF isoform 2.
    
 0.578
PTPRS
PTPRS isoform 2.
    
 0.578
ERC1
ELKS/RAB6-interacting/CAST family member 1.
   
 
 0.578
MPP1
55 kDa erythrocyte membrane protein; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). Belongs to the MAGUK family.
    
 0.571
PTPRE
Receptor-type tyrosine-protein phosphatase.
    
 0.544
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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