Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LUMLUM isoform 1. (338 aa)    
Predicted Functional Partners:
COL1A2
COL1A2 isoform 1.
   
 0.994
COL3A1
COL3A1 isoform 2.
   
 0.976
FBN1
FBN1 isoform 1.
   
 0.956
DCN
Decorin; May affect the rate of fibrils formation.
  
  
0.947
COL1A1
COL1A1 isoform 2.
   
 0.943
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.933
FASLG
FASLG isoform 1; Belongs to the tumor necrosis factor family.
    
  0.901
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
     
  0.901
OGN
Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
   
 
0.854
CHD6
Chromodomain helicase DNA binding protein 6.
    
 
 0.839
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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