NR1H4 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000024510	MED1	ENSPPYP00000024510	ENSPPYP00000009539	annotation not available	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	0.663
ENSPPYP00000024510	NCOA1	ENSPPYP00000024510	ENSPPYP00000014068	annotation not available	Nuclear receptor coactivator.	0.824
ENSPPYP00000024510	NCOA2	ENSPPYP00000024510	ENSPPYP00000024008	annotation not available	Nuclear receptor coactivator.	0.920
ENSPPYP00000024510	NCOR1	ENSPPYP00000024510	ENSPPYP00000009011	annotation not available	NCOR1 isoform 1.	0.540
ENSPPYP00000024510	NR1H4	ENSPPYP00000024510	ENSPPYP00000005555	annotation not available	NR1H4 isoform 5.	0.884
ENSPPYP00000024510	PPARGC1A	ENSPPYP00000024510	ENSPPYP00000016357	annotation not available	PPARG coactivator 1 alpha.	0.663
ENSPPYP00000024510	RXRA	ENSPPYP00000024510	ENSPPYP00000022147	annotation not available	RXRA isoform 2.	0.916
FABP6	FGF19	ENSPPYP00000017910	ENSPPYP00000003433	FABP6 isoform 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.446
FABP6	NCOA2	ENSPPYP00000017910	ENSPPYP00000024008	FABP6 isoform 3.	Nuclear receptor coactivator.	0.415
FABP6	NR0B2	ENSPPYP00000017910	ENSPPYP00000001932	FABP6 isoform 3.	Nuclear receptor subfamily 0 group B member 2.	0.640
FABP6	NR1H4	ENSPPYP00000017910	ENSPPYP00000005555	FABP6 isoform 3.	NR1H4 isoform 5.	0.817
FGF19	FABP6	ENSPPYP00000003433	ENSPPYP00000017910	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	FABP6 isoform 3.	0.446
FGF19	NR0B2	ENSPPYP00000003433	ENSPPYP00000001932	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Nuclear receptor subfamily 0 group B member 2.	0.556
FGF19	NR1H4	ENSPPYP00000003433	ENSPPYP00000005555	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	NR1H4 isoform 5.	0.866
MED1	ENSPPYP00000024510	ENSPPYP00000009539	ENSPPYP00000024510	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	annotation not available	0.663
MED1	NCOA1	ENSPPYP00000009539	ENSPPYP00000014068	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	Nuclear receptor coactivator.	0.663
MED1	NCOA2	ENSPPYP00000009539	ENSPPYP00000024008	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	Nuclear receptor coactivator.	0.664
MED1	NCOR1	ENSPPYP00000009539	ENSPPYP00000009011	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	NCOR1 isoform 1.	0.599
MED1	NR0B2	ENSPPYP00000009539	ENSPPYP00000001932	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	Nuclear receptor subfamily 0 group B member 2.	0.646
MED1	NR1H4	ENSPPYP00000009539	ENSPPYP00000005555	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	NR1H4 isoform 5.	0.845