STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKAP4CKAP4 isoform 3. (475 aa)    
Predicted Functional Partners:
DKK1
Dickkopf-like protein 1.
   
 
 0.834
ZDHHC2
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.824
ZDHHC20
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.557
ZDHHC15
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.557
FAM20C
FAM20C isoform 1.
    
  0.524
DDX42
ATP-dependent RNA helicase DDX42; ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby c [...]
    
 
 0.519
RND2
RND2 isoform 1.
   
 
  0.501
RND3
Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
   
 0.499
ZDHHC16
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.498
CR201_G0003959
MYCT1 isoform 2.
      
 0.497
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.