CKAP4 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKAP4	CR201_G0019731	ENSPPYP00000005595	ENSPPYP00000011992	CKAP4 isoform 3.	RRBP1 isoform 2.	0.673
CKAP4	ENSPPYP00000001345	ENSPPYP00000005595	ENSPPYP00000001345	CKAP4 isoform 3.	annotation not available	0.665
CKAP4	FAM20C	ENSPPYP00000005595	ENSPPYP00000019375	CKAP4 isoform 3.	FAM20C isoform 1.	0.740
CKAP4	HSP90B1	ENSPPYP00000005595	ENSPPYP00000023483	CKAP4 isoform 3.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.786
CKAP4	HSPA5	ENSPPYP00000005595	ENSPPYP00000021973	CKAP4 isoform 3.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.856
CKAP4	RND2	ENSPPYP00000005595	ENSPPYP00000009405	CKAP4 isoform 3.	RND2 isoform 1.	0.691
CKAP4	RND3	ENSPPYP00000005595	ENSPPYP00000014334	CKAP4 isoform 3.	Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.	0.707
CKAP4	ZDHHC15	ENSPPYP00000005595	ENSPPYP00000022929	CKAP4 isoform 3.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.678
CKAP4	ZDHHC2	ENSPPYP00000005595	ENSPPYP00000020596	CKAP4 isoform 3.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.868
CKAP4	ZDHHC20	ENSPPYP00000005595	ENSPPYP00000005925	CKAP4 isoform 3.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.678
CR201_G0019731	CKAP4	ENSPPYP00000011992	ENSPPYP00000005595	RRBP1 isoform 2.	CKAP4 isoform 3.	0.673
ENSPPYP00000001345	CKAP4	ENSPPYP00000001345	ENSPPYP00000005595	annotation not available	CKAP4 isoform 3.	0.665
ENSPPYP00000001345	FAM20C	ENSPPYP00000001345	ENSPPYP00000019375	annotation not available	FAM20C isoform 1.	0.555
ENSPPYP00000001345	HSPA5	ENSPPYP00000001345	ENSPPYP00000021973	annotation not available	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.991
FAM20C	CKAP4	ENSPPYP00000019375	ENSPPYP00000005595	FAM20C isoform 1.	CKAP4 isoform 3.	0.740
FAM20C	ENSPPYP00000001345	ENSPPYP00000019375	ENSPPYP00000001345	FAM20C isoform 1.	annotation not available	0.555
FAM20C	HSP90B1	ENSPPYP00000019375	ENSPPYP00000023483	FAM20C isoform 1.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.555
HSP90B1	CKAP4	ENSPPYP00000023483	ENSPPYP00000005595	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	CKAP4 isoform 3.	0.786
HSP90B1	FAM20C	ENSPPYP00000023483	ENSPPYP00000019375	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	FAM20C isoform 1.	0.555
HSP90B1	HSPA5	ENSPPYP00000023483	ENSPPYP00000021973	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.997