node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP2A1 | ATP2A2 | ENSPPYP00000008168 | ENSPPYP00000005644 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.909 |
ATP2A1 | ATP2A3 | ENSPPYP00000008168 | ENSPPYP00000008813 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.901 |
ATP2A1 | ATP2B1 | ENSPPYP00000008168 | ENSPPYP00000005496 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.567 |
ATP2A1 | ATP2B2 | ENSPPYP00000008168 | ENSPPYP00000015267 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.568 |
ATP2A1 | ATP2B4 | ENSPPYP00000008168 | ENSPPYP00000000364 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.569 |
ATP2A1 | PLN | ENSPPYP00000008168 | ENSPPYP00000020960 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.982 |
ATP2A1 | RORA | ENSPPYP00000008168 | ENSPPYP00000007402 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | RORA isoform 12. | 0.900 |
ATP2A1 | RYR2 | ENSPPYP00000008168 | ENSPPYP00000000078 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | RYR2 isoform 1. | 0.428 |
ATP2A1 | SLN | ENSPPYP00000008168 | ENSPPYP00000004393 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | SLN isoform 1. | 0.916 |
ATP2A1 | TNNI2 | ENSPPYP00000008168 | ENSPPYP00000003385 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Troponin I2, fast skeletal type. | 0.601 |
ATP2A2 | ATP2A1 | ENSPPYP00000005644 | ENSPPYP00000008168 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.909 |
ATP2A2 | ATP2A3 | ENSPPYP00000005644 | ENSPPYP00000008813 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.904 |
ATP2A2 | ATP2B1 | ENSPPYP00000005644 | ENSPPYP00000005496 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.695 |
ATP2A2 | ATP2B2 | ENSPPYP00000005644 | ENSPPYP00000015267 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.693 |
ATP2A2 | ATP2B4 | ENSPPYP00000005644 | ENSPPYP00000000364 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.688 |
ATP2A2 | PLN | ENSPPYP00000005644 | ENSPPYP00000020960 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.993 |
ATP2A2 | RORA | ENSPPYP00000005644 | ENSPPYP00000007402 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | RORA isoform 12. | 0.900 |
ATP2A2 | RYR2 | ENSPPYP00000005644 | ENSPPYP00000000078 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | RYR2 isoform 1. | 0.719 |
ATP2A2 | SLN | ENSPPYP00000005644 | ENSPPYP00000004393 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | SLN isoform 1. | 0.913 |
ATP2A2 | TNNI2 | ENSPPYP00000005644 | ENSPPYP00000003385 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Troponin I2, fast skeletal type. | 0.716 |