Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYL2MYL2 isoform 2. (146 aa)    
Predicted Functional Partners:
MYL3
Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium (By similarity).
   
 0.998
MB
Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
   
 
 0.995
MYH7
MYH7 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.992
MYL4
Myosin light chain 4.
   
 0.980
MYH14
MYH14 isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.975
MYLK
MYLK isoform 5.
   
 0.964
MYL6B
Myosin light chain 6B.
   
0.956
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.956
MYLK3
Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
   
 0.954
TTN
TTN isoform 4.
   
 0.953
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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