| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | ASL | ENSPPYP00000002911 | ENSPPYP00000019643 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Argininosuccinate lyase isoform X1. | 0.684 |
| ALDH18A1 | ASS1 | ENSPPYP00000002911 | ENSPPYP00000022070 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | ASS1 isoform 1. | 0.665 |
| ALDH18A1 | CR201_G0001086 | ENSPPYP00000002911 | ENSPPYP00000005671 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | TMEM116 isoform 9. | 0.703 |
| ALDH18A1 | DHODH | ENSPPYP00000002911 | ENSPPYP00000008492 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | 0.512 |
| ALDH18A1 | DPYD | ENSPPYP00000002911 | ENSPPYP00000001308 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | 0.680 |
| ALDH18A1 | ENSPPYP00000020084 | ENSPPYP00000002911 | ENSPPYP00000020084 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | annotation not available | 0.665 |
| ALDH18A1 | GART | ENSPPYP00000002911 | ENSPPYP00000012701 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.777 |
| ALDH18A1 | OTC | ENSPPYP00000002911 | ENSPPYP00000022656 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.624 |
| ALDH18A1 | UMPS | ENSPPYP00000002911 | ENSPPYP00000015062 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.522 |
| ASL | ALDH18A1 | ENSPPYP00000019643 | ENSPPYP00000002911 | Argininosuccinate lyase isoform X1. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.684 |
| ASL | ASS1 | ENSPPYP00000019643 | ENSPPYP00000022070 | Argininosuccinate lyase isoform X1. | ASS1 isoform 1. | 0.995 |
| ASL | CR201_G0001086 | ENSPPYP00000019643 | ENSPPYP00000005671 | Argininosuccinate lyase isoform X1. | TMEM116 isoform 9. | 0.710 |
| ASL | ENSPPYP00000020084 | ENSPPYP00000019643 | ENSPPYP00000020084 | Argininosuccinate lyase isoform X1. | annotation not available | 0.957 |
| ASL | GART | ENSPPYP00000019643 | ENSPPYP00000012701 | Argininosuccinate lyase isoform X1. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.557 |
| ASL | OTC | ENSPPYP00000019643 | ENSPPYP00000022656 | Argininosuccinate lyase isoform X1. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.849 |
| ASL | UMPS | ENSPPYP00000019643 | ENSPPYP00000015062 | Argininosuccinate lyase isoform X1. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.578 |
| ASS1 | ALDH18A1 | ENSPPYP00000022070 | ENSPPYP00000002911 | ASS1 isoform 1. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.665 |
| ASS1 | ASL | ENSPPYP00000022070 | ENSPPYP00000019643 | ASS1 isoform 1. | Argininosuccinate lyase isoform X1. | 0.995 |
| ASS1 | CR201_G0001086 | ENSPPYP00000022070 | ENSPPYP00000005671 | ASS1 isoform 1. | TMEM116 isoform 9. | 0.655 |
| ASS1 | OTC | ENSPPYP00000022070 | ENSPPYP00000022656 | ASS1 isoform 1. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.992 |
