STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX1DTX1 isoform 1. (599 aa)    
Predicted Functional Partners:
NOTCH3
NOTCH3 isoform 1.
    
 0.953
NOTCH4
NOTCH4 isoform 1.
    
 0.934
NOTCH2
NOTCH2 isoform 2.
    
 0.926
NOTCH1
NOTCH1 isoform 1.
    
 0.903
WWP2
E3 ubiquitin-protein ligase.
    
 0.725
ITCH
E3 ubiquitin-protein ligase.
    
 0.725
WWP1
E3 ubiquitin-protein ligase.
    
 0.725
DNER
DNER isoform 1.
   
 0.690
ENSPPYP00000018739
annotation not available
    
 0.579
ANK1
Ankyrin-1 isoform X1.
    
 0.577
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.