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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CR201_G0000922PXN isoform 2; Belongs to the paxillin family. (381 aa)    
Predicted Functional Partners:
VCL
VCL isoform 2.
   
 0.999
TLN1
TLN1 isoform 1.
   
 0.998
PARVA
PARVA isoform 1.
   
 0.997
PTK2
PTK2 isoform 11; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.996
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 0.995
SRC
Tyrosine-protein kinase.
   
 0.992
PTK2B
PTK2B isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.991
CR201_G0033575
GIT1 isoform 13.
    
 
 0.987
PARVB
Parvin beta.
   
 0.981
TLN2
TLN2 isoform 1.
   
 0.980
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.