CR201_G0050812 protein (Pongo abelii) - STRING interaction network

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Score

CR201_G0050812

EEF1D isoform 18. (135 aa)

Predicted Functional Partners:

EEF1G

0.999

ENSPPYP00000005601

0.925

EEF1B2

0.917

VARS1

0.903

EEF1A1

0.830

EEF1A1-2

0.830

RPL23

0.758

RPS3A

0.757

EEF1A2

0.753

RPS3

0.742

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0050812	EEF1A1	ENSPPYP00000005991	ENSPPYP00000018935	EEF1D isoform 18.	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.830
CR201_G0050812	EEF1A1-2	ENSPPYP00000005991	ENSPPYP00000023822	EEF1D isoform 18.	Pongo abelii eukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA.	0.830
CR201_G0050812	EEF1A2	ENSPPYP00000005991	ENSPPYP00000012552	EEF1D isoform 18.	EEF1A2 isoform 3.	0.753
CR201_G0050812	EEF1B2	ENSPPYP00000005991	ENSPPYP00000014648	EEF1D isoform 18.	Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family.	0.917
CR201_G0050812	EEF1G	ENSPPYP00000005991	ENSPPYP00000023853	EEF1D isoform 18.	EEF1G isoform 1.	0.999
CR201_G0050812	ENSPPYP00000005601	ENSPPYP00000005991	ENSPPYP00000005601	EEF1D isoform 18.	annotation not available	0.925
CR201_G0050812	RPL23	ENSPPYP00000005991	ENSPPYP00000009553	EEF1D isoform 18.	60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.	0.758
CR201_G0050812	RPS3	ENSPPYP00000005991	ENSPPYP00000004215	EEF1D isoform 18.	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]	0.742
CR201_G0050812	RPS3A	ENSPPYP00000005991	ENSPPYP00000023498	EEF1D isoform 18.	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.	0.757
CR201_G0050812	VARS1	ENSPPYP00000005991	ENSPPYP00000018404	EEF1D isoform 18.	VARS isoform 1; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.903
EEF1A1	CR201_G0050812	ENSPPYP00000018935	ENSPPYP00000005991	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	EEF1D isoform 18.	0.830
EEF1A1	EEF1A2	ENSPPYP00000018935	ENSPPYP00000012552	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	EEF1A2 isoform 3.	0.942
EEF1A1	EEF1B2	ENSPPYP00000018935	ENSPPYP00000014648	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family.	0.965
EEF1A1	EEF1G	ENSPPYP00000018935	ENSPPYP00000023853	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	EEF1G isoform 1.	0.997
EEF1A1	ENSPPYP00000005601	ENSPPYP00000018935	ENSPPYP00000005601	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	annotation not available	0.925
EEF1A1	RPL23	ENSPPYP00000018935	ENSPPYP00000009553	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.	0.853
EEF1A1	RPS3	ENSPPYP00000018935	ENSPPYP00000004215	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]	0.826
EEF1A1	RPS3A	ENSPPYP00000018935	ENSPPYP00000023498	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.	0.963
EEF1A1	VARS1	ENSPPYP00000018935	ENSPPYP00000018404	Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	VARS isoform 1; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.876
EEF1A1-2	CR201_G0050812	ENSPPYP00000023822	ENSPPYP00000005991	Pongo abelii eukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA.	EEF1D isoform 18.	0.830