| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGT | CFI | ENSPPYP00000000122 | ENSPPYP00000016746 | AGT isoform 1; Belongs to the serpin family. | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | 0.420 |
| AGT | CPB1 | ENSPPYP00000000122 | ENSPPYP00000015871 | AGT isoform 1; Belongs to the serpin family. | CPB1 isoform 1. | 0.560 |
| AGT | CPB2 | ENSPPYP00000000122 | ENSPPYP00000006087 | AGT isoform 1; Belongs to the serpin family. | Carboxypeptidase B2. | 0.737 |
| AGT | F2 | ENSPPYP00000000122 | ENSPPYP00000003807 | AGT isoform 1; Belongs to the serpin family. | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). | 0.669 |
| AGT | SERPINC1 | ENSPPYP00000000122 | ENSPPYP00000000566 | AGT isoform 1; Belongs to the serpin family. | Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity). | 0.571 |
| CFI | AGT | ENSPPYP00000016746 | ENSPPYP00000000122 | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | AGT isoform 1; Belongs to the serpin family. | 0.420 |
| CFI | CPB2 | ENSPPYP00000016746 | ENSPPYP00000006087 | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | Carboxypeptidase B2. | 0.740 |
| CFI | CPN1 | ENSPPYP00000016746 | ENSPPYP00000023842 | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | CPN1 isoform 1. | 0.570 |
| CFI | F12 | ENSPPYP00000016746 | ENSPPYP00000018007 | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | Coagulation factor XII. | 0.613 |
| CFI | F13B | ENSPPYP00000016746 | ENSPPYP00000024425 | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | F13B isoform 1. | 0.434 |
| CFI | F2 | ENSPPYP00000016746 | ENSPPYP00000003807 | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). | 0.476 |
| CFI | THBD | ENSPPYP00000016746 | ENSPPYP00000012026 | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | THBD isoform 1. | 0.519 |
| CPB1 | AGT | ENSPPYP00000015871 | ENSPPYP00000000122 | CPB1 isoform 1. | AGT isoform 1; Belongs to the serpin family. | 0.560 |
| CPB1 | CPB2 | ENSPPYP00000015871 | ENSPPYP00000006087 | CPB1 isoform 1. | Carboxypeptidase B2. | 0.903 |
| CPB1 | CPE | ENSPPYP00000015871 | ENSPPYP00000016961 | CPB1 isoform 1. | Carboxypeptidase E. | 0.576 |
| CPB1 | CPN1 | ENSPPYP00000015871 | ENSPPYP00000023842 | CPB1 isoform 1. | CPN1 isoform 1. | 0.715 |
| CPB1 | SERPINC1 | ENSPPYP00000015871 | ENSPPYP00000000566 | CPB1 isoform 1. | Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity). | 0.427 |
| CPB2 | AGT | ENSPPYP00000006087 | ENSPPYP00000000122 | Carboxypeptidase B2. | AGT isoform 1; Belongs to the serpin family. | 0.737 |
| CPB2 | CFI | ENSPPYP00000006087 | ENSPPYP00000016746 | Carboxypeptidase B2. | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | 0.740 |
| CPB2 | CPB1 | ENSPPYP00000006087 | ENSPPYP00000015871 | Carboxypeptidase B2. | CPB1 isoform 1. | 0.903 |
