LRRC63 protein (Pongo abelii) - STRING interaction network

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LRRC63

LRRC63 isoform 3. (504 aa)

Predicted Functional Partners:

CUL5

0.647

CDO1

0.634

ELOC

0.541

ENSPPYP00000023677

0.541

LRRC26

0.529

CPN2

0.511

SUCO

0.491

MIS12

0.485

CR201_G0051802

0.479

NEDD8

0.478

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDO1	CUL5	ENSPPYP00000017558	ENSPPYP00000004398	Cysteine dioxygenase type 1.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.532
CDO1	ELOC	ENSPPYP00000017558	ENSPPYP00000020952	Cysteine dioxygenase type 1.	ELOC isoform 10; Belongs to the SKP1 family.	0.494
CDO1	ENSPPYP00000023677	ENSPPYP00000017558	ENSPPYP00000023677	Cysteine dioxygenase type 1.	annotation not available	0.494
CDO1	LRRC63	ENSPPYP00000017558	ENSPPYP00000006089	Cysteine dioxygenase type 1.	LRRC63 isoform 3.	0.634
CDO1	NEDD8	ENSPPYP00000017558	ENSPPYP00000006472	Cysteine dioxygenase type 1.	Ubiquitin-like protein Nedd8.	0.532
CPN2	LRRC63	ENSPPYP00000024642	ENSPPYP00000006089	CPN2 isoform 1.	LRRC63 isoform 3.	0.511
CR201_G0051802	LRRC63	ENSPPYP00000014957	ENSPPYP00000006089	CCDC74B isoform 2.	LRRC63 isoform 3.	0.479
CUL5	CDO1	ENSPPYP00000004398	ENSPPYP00000017558	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Cysteine dioxygenase type 1.	0.532
CUL5	ELOC	ENSPPYP00000004398	ENSPPYP00000020952	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	ELOC isoform 10; Belongs to the SKP1 family.	0.997
CUL5	ENSPPYP00000023677	ENSPPYP00000004398	ENSPPYP00000023677	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	annotation not available	0.973
CUL5	LRRC63	ENSPPYP00000004398	ENSPPYP00000006089	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	LRRC63 isoform 3.	0.647
CUL5	NEDD8	ENSPPYP00000004398	ENSPPYP00000006472	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Ubiquitin-like protein Nedd8.	0.974
ELOC	CDO1	ENSPPYP00000020952	ENSPPYP00000017558	ELOC isoform 10; Belongs to the SKP1 family.	Cysteine dioxygenase type 1.	0.494
ELOC	CUL5	ENSPPYP00000020952	ENSPPYP00000004398	ELOC isoform 10; Belongs to the SKP1 family.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.997
ELOC	ENSPPYP00000023677	ENSPPYP00000020952	ENSPPYP00000023677	ELOC isoform 10; Belongs to the SKP1 family.	annotation not available	0.801
ELOC	LRRC63	ENSPPYP00000020952	ENSPPYP00000006089	ELOC isoform 10; Belongs to the SKP1 family.	LRRC63 isoform 3.	0.541
ELOC	NEDD8	ENSPPYP00000020952	ENSPPYP00000006472	ELOC isoform 10; Belongs to the SKP1 family.	Ubiquitin-like protein Nedd8.	0.907
ENSPPYP00000023677	CDO1	ENSPPYP00000023677	ENSPPYP00000017558	annotation not available	Cysteine dioxygenase type 1.	0.494
ENSPPYP00000023677	CUL5	ENSPPYP00000023677	ENSPPYP00000004398	annotation not available	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.973
ENSPPYP00000023677	ELOC	ENSPPYP00000023677	ENSPPYP00000020952	annotation not available	ELOC isoform 10; Belongs to the SKP1 family.	0.801