STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDH9PCDH9 isoform 2. (1237 aa)    
Predicted Functional Partners:
SETD4
SET domain containing 4.
      
 0.866
SLC37A3
SLC37A3 isoform 3.
      
 0.866
SLC5A7
SLC5A7 isoform 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.862
PPP1R8
Protein phosphatase 1 regulatory subunit 8.
      
 0.715
PPP1R10
Protein phosphatase 1 regulatory subunit 10.
     
 0.690
SGCD
Sarcoglycan delta.
      
 0.656
PPP1R11
PPP1R11 isoform 1.
      
 0.649
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
  
 0.647
CASK
CASK isoform 2; Belongs to the MAGUK family.
    
 0.607
RIOK2
RIOK2 isoform 1.
      
 0.581
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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