Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLN5T0025243 isoform 1. (378 aa)    
Predicted Functional Partners:
CLN6
CLN6 transmembrane ER protein.
  
 
 
 0.841
CRISP1
Cysteine rich secretory protein 1; Belongs to the CRISP family.
      
 0.826
CTSH
CTSH isoform 1; Belongs to the peptidase C1 family.
      
 0.814
ANPEP
Aminopeptidase.
      
 0.814
MYH9
MYH9 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.814
CLN3
Battenin.
    
 
 0.804
PPT1
Palmitoyl-protein thioesterase 1.
      
 0.740
MFSD8
MFSD8 isoform 10.
      
 0.692
PATE1
Prostate and testis expressed 1.
      
 0.659
HSPA8
Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]
      
 0.654
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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