ENSPPYP00000006214 protein (Pongo abelii) - STRING interaction network

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[Homology]

Score

ENSPPYP00000006214

annotation not available (312 aa)

Predicted Functional Partners:

HSPA8

0.990

HSPA6

0.983

HSPA4

0.983

SUGT1

0.974

HSP90B1

0.974

AKT1

0.972

HSPA2

0.969

HSPD1

0.967

HSPA1L

0.966

HSPA1A

0.966

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	ENSPPYP00000006214	ENSPPYP00000007036	ENSPPYP00000006214	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	annotation not available	0.972
AKT1	HSP90B1	ENSPPYP00000007036	ENSPPYP00000023483	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.933
AKT1	HSPA2	ENSPPYP00000007036	ENSPPYP00000006709	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.	0.401
AKT1	HSPA4	ENSPPYP00000007036	ENSPPYP00000017643	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.	0.502
AKT1	HSPA8	ENSPPYP00000007036	ENSPPYP00000004564	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]	0.540
ENSPPYP00000006214	AKT1	ENSPPYP00000006214	ENSPPYP00000007036	annotation not available	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.972
ENSPPYP00000006214	HSP90B1	ENSPPYP00000006214	ENSPPYP00000023483	annotation not available	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.974
ENSPPYP00000006214	HSPA1A	ENSPPYP00000006214	ENSPPYP00000018408	annotation not available	Heat shock 70 kDa protein 1; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...]	0.966
ENSPPYP00000006214	HSPA1L	ENSPPYP00000006214	ENSPPYP00000018406	annotation not available	Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.	0.966
ENSPPYP00000006214	HSPA2	ENSPPYP00000006214	ENSPPYP00000006709	annotation not available	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.	0.969
ENSPPYP00000006214	HSPA4	ENSPPYP00000006214	ENSPPYP00000017643	annotation not available	Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.	0.983
ENSPPYP00000006214	HSPA6	ENSPPYP00000006214	ENSPPYP00000000695	annotation not available	Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.	0.983
ENSPPYP00000006214	HSPA8	ENSPPYP00000006214	ENSPPYP00000004564	annotation not available	Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]	0.990
ENSPPYP00000006214	HSPD1	ENSPPYP00000006214	ENSPPYP00000014577	annotation not available	60 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...]	0.967
ENSPPYP00000006214	SUGT1	ENSPPYP00000006214	ENSPPYP00000006144	annotation not available	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.974
HSP90B1	AKT1	ENSPPYP00000023483	ENSPPYP00000007036	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.933
HSP90B1	ENSPPYP00000006214	ENSPPYP00000023483	ENSPPYP00000006214	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	annotation not available	0.974
HSP90B1	HSPA1A	ENSPPYP00000023483	ENSPPYP00000018408	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	Heat shock 70 kDa protein 1; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...]	0.985
HSP90B1	HSPA1L	ENSPPYP00000023483	ENSPPYP00000018406	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.	0.976
HSP90B1	HSPA2	ENSPPYP00000023483	ENSPPYP00000006709	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.	0.966