| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARID4B | BRMS1L | ENSPPYP00000000098 | ENSPPYP00000006531 | AT-rich interaction domain 4B. | BRMS1 like transcriptional repressor. | 0.899 |
| ARID4B | HDAC1 | ENSPPYP00000000098 | ENSPPYP00000001838 | AT-rich interaction domain 4B. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.929 |
| ARID4B | HDAC2 | ENSPPYP00000000098 | ENSPPYP00000018964 | AT-rich interaction domain 4B. | Histone deacetylase 2. | 0.905 |
| ARID4B | ING1 | ENSPPYP00000000098 | ENSPPYP00000006275 | AT-rich interaction domain 4B. | Inhibitor of growth protein. | 0.753 |
| ARID4B | RBBP4 | ENSPPYP00000000098 | ENSPPYP00000001831 | AT-rich interaction domain 4B. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.951 |
| ARID4B | RBBP7 | ENSPPYP00000000098 | ENSPPYP00000022548 | AT-rich interaction domain 4B. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.948 |
| ARID4B | SAP30 | ENSPPYP00000000098 | ENSPPYP00000016988 | AT-rich interaction domain 4B. | Uncharacterized protein. | 0.994 |
| ARID4B | SIN3A | ENSPPYP00000000098 | ENSPPYP00000007556 | AT-rich interaction domain 4B. | SIN3 transcription regulator family member A. | 0.935 |
| ARID4B | SINHCAF | ENSPPYP00000000098 | ENSPPYP00000005017 | AT-rich interaction domain 4B. | SIN3-HDAC complex-associated factor; Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway. Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is crucial for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming. | 0.853 |
| BRMS1L | ARID4B | ENSPPYP00000006531 | ENSPPYP00000000098 | BRMS1 like transcriptional repressor. | AT-rich interaction domain 4B. | 0.899 |
| BRMS1L | HDAC1 | ENSPPYP00000006531 | ENSPPYP00000001838 | BRMS1 like transcriptional repressor. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.898 |
| BRMS1L | HDAC2 | ENSPPYP00000006531 | ENSPPYP00000018964 | BRMS1 like transcriptional repressor. | Histone deacetylase 2. | 0.806 |
| BRMS1L | ING1 | ENSPPYP00000006531 | ENSPPYP00000006275 | BRMS1 like transcriptional repressor. | Inhibitor of growth protein. | 0.744 |
| BRMS1L | RBBP4 | ENSPPYP00000006531 | ENSPPYP00000001831 | BRMS1 like transcriptional repressor. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.879 |
| BRMS1L | RBBP7 | ENSPPYP00000006531 | ENSPPYP00000022548 | BRMS1 like transcriptional repressor. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.880 |
| BRMS1L | SAP30 | ENSPPYP00000006531 | ENSPPYP00000016988 | BRMS1 like transcriptional repressor. | Uncharacterized protein. | 0.965 |
| BRMS1L | SIN3A | ENSPPYP00000006531 | ENSPPYP00000007556 | BRMS1 like transcriptional repressor. | SIN3 transcription regulator family member A. | 0.887 |
| BRMS1L | SINHCAF | ENSPPYP00000006531 | ENSPPYP00000005017 | BRMS1 like transcriptional repressor. | SIN3-HDAC complex-associated factor; Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway. Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is crucial for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming. | 0.839 |
| HDAC1 | ARID4B | ENSPPYP00000001838 | ENSPPYP00000000098 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | AT-rich interaction domain 4B. | 0.929 |
| HDAC1 | BRMS1L | ENSPPYP00000001838 | ENSPPYP00000006531 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | BRMS1 like transcriptional repressor. | 0.898 |
