MCF2L protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Knowledge-based Evidence

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	MCF2L	ENSPPYP00000002031	ENSPPYP00000006288	Cell division cycle 42.	MCF2L isoform 10.	0.900
CDC42	RAC1	ENSPPYP00000002031	ENSPPYP00000019439	Cell division cycle 42.	Rac family small GTPase 1.	0.993
CDC42	RAC2	ENSPPYP00000002031	ENSPPYP00000013154	Cell division cycle 42.	Rac family small GTPase 2.	0.836
CDC42	RAC3	ENSPPYP00000002031	ENSPPYP00000009837	Cell division cycle 42.	RAC3 isoform 1.	0.859
CDC42	RHOA	ENSPPYP00000002031	ENSPPYP00000015522	Cell division cycle 42.	Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...]	0.809
CDC42	RHOC	ENSPPYP00000002031	ENSPPYP00000001186	Cell division cycle 42.	Rho-related GTP-binding protein RhoC; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells (By similarity).	0.755
CDC42	RHOC-2	ENSPPYP00000002031	ENSPPYP00000011947	Cell division cycle 42.	RHOA isoform 3.	0.629
CDC42	RHOG	ENSPPYP00000002031	ENSPPYP00000004149	Cell division cycle 42.	Ras homolog family member G.	0.743
DUS4L	MCF2L	ENSPPYP00000020065	ENSPPYP00000006288	tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.	MCF2L isoform 10.	0.621
IL1RAPL1	MCF2L	ENSPPYP00000022613	ENSPPYP00000006288	IL1RAPL1 isoform 1.	MCF2L isoform 10.	0.721
MCF2L	CDC42	ENSPPYP00000006288	ENSPPYP00000002031	MCF2L isoform 10.	Cell division cycle 42.	0.900
MCF2L	DUS4L	ENSPPYP00000006288	ENSPPYP00000020065	MCF2L isoform 10.	tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.	0.621
MCF2L	IL1RAPL1	ENSPPYP00000006288	ENSPPYP00000022613	MCF2L isoform 10.	IL1RAPL1 isoform 1.	0.721
MCF2L	RAC1	ENSPPYP00000006288	ENSPPYP00000019439	MCF2L isoform 10.	Rac family small GTPase 1.	0.840
MCF2L	RAC2	ENSPPYP00000006288	ENSPPYP00000013154	MCF2L isoform 10.	Rac family small GTPase 2.	0.620
MCF2L	RAC3	ENSPPYP00000006288	ENSPPYP00000009837	MCF2L isoform 10.	RAC3 isoform 1.	0.703
MCF2L	RHOA	ENSPPYP00000006288	ENSPPYP00000015522	MCF2L isoform 10.	Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...]	0.864
MCF2L	RHOC	ENSPPYP00000006288	ENSPPYP00000001186	MCF2L isoform 10.	Rho-related GTP-binding protein RhoC; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells (By similarity).	0.743
MCF2L	RHOC-2	ENSPPYP00000006288	ENSPPYP00000011947	MCF2L isoform 10.	RHOA isoform 3.	0.715
MCF2L	RHOG	ENSPPYP00000006288	ENSPPYP00000004149	MCF2L isoform 10.	Ras homolog family member G.	0.575