| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALYREF | CASC3 | ENSPPYP00000009820 | ENSPPYP00000009515 | Aly/REF export factor. | CASC3 isoform 1. | 0.901 |
| ALYREF | EIF4A3 | ENSPPYP00000009820 | ENSPPYP00000009779 | Aly/REF export factor. | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | 0.995 |
| ALYREF | MAGOH | ENSPPYP00000009820 | ENSPPYP00000001553 | Aly/REF export factor. | Mago homolog, exon junction complex subunit. | 0.952 |
| ALYREF | NXF1 | ENSPPYP00000009820 | ENSPPYP00000003631 | Aly/REF export factor. | Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1- NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A- containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A- containing mRNA-binding to both [...] | 0.992 |
| ALYREF | RBM8A | ENSPPYP00000009820 | ENSPPYP00000001082 | Aly/REF export factor. | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. | 0.961 |
| ALYREF | SRRM1 | ENSPPYP00000009820 | ENSPPYP00000001983 | Aly/REF export factor. | Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with lo [...] | 0.984 |
| ALYREF | UPF1 | ENSPPYP00000009820 | ENSPPYP00000010923 | Aly/REF export factor. | UPF1 isoform 2. | 0.949 |
| ALYREF | UPF2 | ENSPPYP00000009820 | ENSPPYP00000002423 | Aly/REF export factor. | UPF2 isoform 1. | 0.600 |
| ALYREF | UPF3A | ENSPPYP00000009820 | ENSPPYP00000006310 | Aly/REF export factor. | UPF3A regulator of nonsense mediated mRNA decay. | 0.987 |
| CASC3 | ALYREF | ENSPPYP00000009515 | ENSPPYP00000009820 | CASC3 isoform 1. | Aly/REF export factor. | 0.901 |
| CASC3 | EIF4A3 | ENSPPYP00000009515 | ENSPPYP00000009779 | CASC3 isoform 1. | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | 0.998 |
| CASC3 | MAGOH | ENSPPYP00000009515 | ENSPPYP00000001553 | CASC3 isoform 1. | Mago homolog, exon junction complex subunit. | 0.993 |
| CASC3 | NXF1 | ENSPPYP00000009515 | ENSPPYP00000003631 | CASC3 isoform 1. | Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1- NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A- containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A- containing mRNA-binding to both [...] | 0.503 |
| CASC3 | RBM8A | ENSPPYP00000009515 | ENSPPYP00000001082 | CASC3 isoform 1. | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. | 0.991 |
| CASC3 | SMG5 | ENSPPYP00000009515 | ENSPPYP00000000838 | CASC3 isoform 1. | SMG5 nonsense mediated mRNA decay factor. | 0.827 |
| CASC3 | SRRM1 | ENSPPYP00000009515 | ENSPPYP00000001983 | CASC3 isoform 1. | Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with lo [...] | 0.726 |
| CASC3 | UPF1 | ENSPPYP00000009515 | ENSPPYP00000010923 | CASC3 isoform 1. | UPF1 isoform 2. | 0.990 |
| CASC3 | UPF2 | ENSPPYP00000009515 | ENSPPYP00000002423 | CASC3 isoform 1. | UPF2 isoform 1. | 0.988 |
| CASC3 | UPF3A | ENSPPYP00000009515 | ENSPPYP00000006310 | CASC3 isoform 1. | UPF3A regulator of nonsense mediated mRNA decay. | 0.982 |
| EIF4A3 | ALYREF | ENSPPYP00000009779 | ENSPPYP00000009820 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | Aly/REF export factor. | 0.995 |
