STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC7A8Large neutral amino acids transporter small subunit 2; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administe [...] (535 aa)    
Predicted Functional Partners:
SLC3A2
Solute carrier family 3 member 2.
   
 0.999
LCN2
LCN2 isoform 1; Belongs to the calycin superfamily. Lipocalin family.
    
   0.753
SLC3A1
SLC3A1 isoform 1.
   
 0.741
SLC43A1
SLC43A1 isoform 1.
   
  
 0.716
SLC16A2
SLC16A2 isoform 2.
      
 0.665
SLC7A5
Solute carrier family 7 member 5.
  
  
0.660
SLC43A2
Large neutral amino acids transporter small subunit 4; Sodium-, chloride, pH-independent high affinity transport of large neutral amino acids.
   
  
 0.584
SLCO1C1
Solute carrier organic anion transporter family member.
   
  
 0.562
ALKBH2
ALKBH2 isoform 3.
   
 0.538
KIAA0513
KIAA0513 isoform 1.
   
 0.538
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.