| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCY4 | ADCY6 | ENSPPYP00000006484 | ENSPPYP00000005099 | Adenylate cyclase type 4 isoform X1. | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.939 |
| ADCY4 | ADCY8 | ENSPPYP00000006484 | ENSPPYP00000021189 | Adenylate cyclase type 4 isoform X1. | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.949 |
| ADCY4 | GNAI2 | ENSPPYP00000006484 | ENSPPYP00000015499 | Adenylate cyclase type 4 isoform X1. | GNAI2 isoform 1. | 0.962 |
| ADCY4 | GNAI3 | ENSPPYP00000006484 | ENSPPYP00000001241 | Adenylate cyclase type 4 isoform X1. | Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] | 0.956 |
| ADCY4 | GNAL | ENSPPYP00000006484 | ENSPPYP00000010095 | Adenylate cyclase type 4 isoform X1. | GNAL isoform 3. | 0.972 |
| ADCY4 | GNAO1 | ENSPPYP00000006484 | ENSPPYP00000008317 | Adenylate cyclase type 4 isoform X1. | GNAO1 isoform 1. | 0.942 |
| ADCY4 | GNAS | ENSPPYP00000006484 | ENSPPYP00000012485 | Adenylate cyclase type 4 isoform X1. | GNAS isoform 2. | 0.982 |
| ADCY4 | PRKACB | ENSPPYP00000006484 | ENSPPYP00000001400 | Adenylate cyclase type 4 isoform X1. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.951 |
| ADCY4 | PRKACG | ENSPPYP00000006484 | ENSPPYP00000021585 | Adenylate cyclase type 4 isoform X1. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.951 |
| ADCY4 | RAPGEF4 | ENSPPYP00000006484 | ENSPPYP00000014442 | Adenylate cyclase type 4 isoform X1. | Rap guanine nucleotide exchange factor 4. | 0.928 |
| ADCY6 | ADCY4 | ENSPPYP00000005099 | ENSPPYP00000006484 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adenylate cyclase type 4 isoform X1. | 0.939 |
| ADCY6 | ADCY8 | ENSPPYP00000005099 | ENSPPYP00000021189 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.951 |
| ADCY6 | GNAI2 | ENSPPYP00000005099 | ENSPPYP00000015499 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAI2 isoform 1. | 0.964 |
| ADCY6 | GNAI3 | ENSPPYP00000005099 | ENSPPYP00000001241 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] | 0.958 |
| ADCY6 | GNAL | ENSPPYP00000005099 | ENSPPYP00000010095 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAL isoform 3. | 0.759 |
| ADCY6 | GNAO1 | ENSPPYP00000005099 | ENSPPYP00000008317 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAO1 isoform 1. | 0.947 |
| ADCY6 | GNAS | ENSPPYP00000005099 | ENSPPYP00000012485 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAS isoform 2. | 0.986 |
| ADCY6 | PRKACB | ENSPPYP00000005099 | ENSPPYP00000001400 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.953 |
| ADCY6 | PRKACG | ENSPPYP00000005099 | ENSPPYP00000021585 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.953 |
| ADCY6 | RAPGEF4 | ENSPPYP00000005099 | ENSPPYP00000014442 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Rap guanine nucleotide exchange factor 4. | 0.941 |
