G2E3 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASH2L	CDCA8	ENSPPYP00000020758	ENSPPYP00000001762	ASH2L isoform 3.	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	0.438
ASH2L	G2E3	ENSPPYP00000020758	ENSPPYP00000006501	ASH2L isoform 3.	G2E3 isoform 1.	0.563
ASH2L	RBBP5	ENSPPYP00000020758	ENSPPYP00000000338	ASH2L isoform 3.	RBBP5 isoform 2.	0.999
CDCA2	CDCA8	ENSPPYP00000020681	ENSPPYP00000001762	Cell division cycle associated 2.	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	0.804
CDCA2	CKAP2	ENSPPYP00000020681	ENSPPYP00000006141	Cell division cycle associated 2.	Cytoskeleton-associated protein 2; Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity).	0.761
CDCA2	DLGAP5	ENSPPYP00000020681	ENSPPYP00000006634	Cell division cycle associated 2.	DLGAP5 isoform 1.	0.916
CDCA2	G2E3	ENSPPYP00000020681	ENSPPYP00000006501	Cell division cycle associated 2.	G2E3 isoform 1.	0.538
CDCA2	GAS2L3	ENSPPYP00000020681	ENSPPYP00000005556	Cell division cycle associated 2.	GAS2L3 isoform 2.	0.645
CDCA2	KIF20B	ENSPPYP00000020681	ENSPPYP00000002863	Cell division cycle associated 2.	KIF20B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.738
CDCA8	ASH2L	ENSPPYP00000001762	ENSPPYP00000020758	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	ASH2L isoform 3.	0.438
CDCA8	CDCA2	ENSPPYP00000001762	ENSPPYP00000020681	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	Cell division cycle associated 2.	0.804
CDCA8	CKAP2	ENSPPYP00000001762	ENSPPYP00000006141	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	Cytoskeleton-associated protein 2; Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity).	0.775
CDCA8	DLGAP5	ENSPPYP00000001762	ENSPPYP00000006634	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	DLGAP5 isoform 1.	0.923
CDCA8	G2E3	ENSPPYP00000001762	ENSPPYP00000006501	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	G2E3 isoform 1.	0.510
CDCA8	GAS2L3	ENSPPYP00000001762	ENSPPYP00000005556	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	GAS2L3 isoform 2.	0.431
CDCA8	KIF20B	ENSPPYP00000001762	ENSPPYP00000002863	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	KIF20B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.840
CDCA8	RBBP5	ENSPPYP00000001762	ENSPPYP00000000338	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	RBBP5 isoform 2.	0.419
CKAP2	CDCA2	ENSPPYP00000006141	ENSPPYP00000020681	Cytoskeleton-associated protein 2; Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity).	Cell division cycle associated 2.	0.761
CKAP2	CDCA8	ENSPPYP00000006141	ENSPPYP00000001762	Cytoskeleton-associated protein 2; Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity).	Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). Belongs to the borealin family.	0.775
CKAP2	DLGAP5	ENSPPYP00000006141	ENSPPYP00000006634	Cytoskeleton-associated protein 2; Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity).	DLGAP5 isoform 1.	0.935