ARHGAP5 protein (Pongo abelii) - STRING interaction network

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Score

ARHGAP5

ARHGAP5 isoform 3. (1502 aa)

Predicted Functional Partners:

SRC

0.946

ARHGAP35

0.906

THY1

0.900

RASA1

0.850

RHOA

0.808

RHOC

0.677

RND2

0.643

RHOC-2

0.642

RND3

0.633

RASAL3

0.627

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP35	ARHGAP5	ENSPPYP00000011368	ENSPPYP00000006512	Rho GTPase activating protein 35.	ARHGAP5 isoform 3.	0.906
ARHGAP35	RASA1	ENSPPYP00000011368	ENSPPYP00000017460	Rho GTPase activating protein 35.	RASA1 isoform 1.	0.989
ARHGAP35	RASAL3	ENSPPYP00000011368	ENSPPYP00000024149	Rho GTPase activating protein 35.	RASAL3 isoform 1.	0.465
ARHGAP35	RHOA	ENSPPYP00000011368	ENSPPYP00000015522	Rho GTPase activating protein 35.	Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...]	0.958
ARHGAP35	RHOC	ENSPPYP00000011368	ENSPPYP00000001186	Rho GTPase activating protein 35.	Rho-related GTP-binding protein RhoC; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells (By similarity).	0.912
ARHGAP35	RHOC-2	ENSPPYP00000011368	ENSPPYP00000011947	Rho GTPase activating protein 35.	RHOA isoform 3.	0.857
ARHGAP35	RND2	ENSPPYP00000011368	ENSPPYP00000009405	Rho GTPase activating protein 35.	RND2 isoform 1.	0.803
ARHGAP35	RND3	ENSPPYP00000011368	ENSPPYP00000014334	Rho GTPase activating protein 35.	Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.	0.877
ARHGAP35	SRC	ENSPPYP00000011368	ENSPPYP00000012270	Rho GTPase activating protein 35.	Tyrosine-protein kinase.	0.971
ARHGAP35	THY1	ENSPPYP00000011368	ENSPPYP00000004545	Rho GTPase activating protein 35.	Thy-1 cell surface antigen.	0.902
ARHGAP5	ARHGAP35	ENSPPYP00000006512	ENSPPYP00000011368	ARHGAP5 isoform 3.	Rho GTPase activating protein 35.	0.906
ARHGAP5	RASA1	ENSPPYP00000006512	ENSPPYP00000017460	ARHGAP5 isoform 3.	RASA1 isoform 1.	0.850
ARHGAP5	RASAL3	ENSPPYP00000006512	ENSPPYP00000024149	ARHGAP5 isoform 3.	RASAL3 isoform 1.	0.627
ARHGAP5	RHOA	ENSPPYP00000006512	ENSPPYP00000015522	ARHGAP5 isoform 3.	Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...]	0.808
ARHGAP5	RHOC	ENSPPYP00000006512	ENSPPYP00000001186	ARHGAP5 isoform 3.	Rho-related GTP-binding protein RhoC; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells (By similarity).	0.677
ARHGAP5	RHOC-2	ENSPPYP00000006512	ENSPPYP00000011947	ARHGAP5 isoform 3.	RHOA isoform 3.	0.642
ARHGAP5	RND2	ENSPPYP00000006512	ENSPPYP00000009405	ARHGAP5 isoform 3.	RND2 isoform 1.	0.643
ARHGAP5	RND3	ENSPPYP00000006512	ENSPPYP00000014334	ARHGAP5 isoform 3.	Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.	0.633
ARHGAP5	SRC	ENSPPYP00000006512	ENSPPYP00000012270	ARHGAP5 isoform 3.	Tyrosine-protein kinase.	0.946
ARHGAP5	THY1	ENSPPYP00000006512	ENSPPYP00000004545	ARHGAP5 isoform 3.	Thy-1 cell surface antigen.	0.900