Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL28Kelch like family member 28. (585 aa)    
Predicted Functional Partners:
KLHL14
KLHL14 isoform 1.
    
  0.807
CUL3
CUL3 isoform 1; Belongs to the cullin family.
    
 0.800
IPP
IPP isoform 1.
    
  0.792
KLHL24
Kelch like family member 24.
   
   0.772
FBXL17
FBXL17 isoform 1.
    
 0.769
KLHL21
Kelch like family member 21.
    
  0.763
KLHL26
KLHL26 isoform 1.
   
  0.753
NUDCD3
NudC domain-containing protein 3.
   
 
 0.723
RNF166
RNF166 isoform 1.
    
 
 0.656
KLHL12
KLHL12 isoform 2.
    
  0.610
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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