VCPKMT protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

VCPKMT

Valosin containing protein lysine methyltransferase. (229 aa)

Predicted Functional Partners:

VCP

0.988

UBXN6

0.928

SPATA5L1

0.745

SPATA5

0.745

METTL18

0.612

EEF1AKMT1

0.587

EEF1AKMT2

0.578

ATPSCKMT

0.541

CSKMT

0.513

EEF1AKNMT

0.508

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATPSCKMT	CSKMT	ENSPPYP00000017137	ENSPPYP00000003646	FAM173B isoform 2.	Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial; Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria. Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methly group per binding event.	0.532
ATPSCKMT	EEF1AKMT1	ENSPPYP00000017137	ENSPPYP00000005918	FAM173B isoform 2.	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.	0.606
ATPSCKMT	EEF1AKMT2	ENSPPYP00000017137	ENSPPYP00000003202	FAM173B isoform 2.	EEF1AKMT2 isoform 2.	0.526
ATPSCKMT	EEF1AKNMT	ENSPPYP00000017137	ENSPPYP00000000590	FAM173B isoform 2.	METTL13 isoform 4.	0.509
ATPSCKMT	METTL18	ENSPPYP00000017137	ENSPPYP00000000611	FAM173B isoform 2.	Methyltransferase like 18.	0.554
ATPSCKMT	VCPKMT	ENSPPYP00000017137	ENSPPYP00000006587	FAM173B isoform 2.	Valosin containing protein lysine methyltransferase.	0.541
CSKMT	ATPSCKMT	ENSPPYP00000003646	ENSPPYP00000017137	Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial; Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria. Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methly group per binding event.	FAM173B isoform 2.	0.532
CSKMT	EEF1AKMT2	ENSPPYP00000003646	ENSPPYP00000003202	Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial; Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria. Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methly group per binding event.	EEF1AKMT2 isoform 2.	0.485
CSKMT	VCPKMT	ENSPPYP00000003646	ENSPPYP00000006587	Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial; Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria. Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methly group per binding event.	Valosin containing protein lysine methyltransferase.	0.513
EEF1AKMT1	ATPSCKMT	ENSPPYP00000005918	ENSPPYP00000017137	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.	FAM173B isoform 2.	0.606
EEF1AKMT1	EEF1AKMT2	ENSPPYP00000005918	ENSPPYP00000003202	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.	EEF1AKMT2 isoform 2.	0.695
EEF1AKMT1	EEF1AKNMT	ENSPPYP00000005918	ENSPPYP00000000590	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.	METTL13 isoform 4.	0.458
EEF1AKMT1	METTL18	ENSPPYP00000005918	ENSPPYP00000000611	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.	Methyltransferase like 18.	0.530
EEF1AKMT1	VCPKMT	ENSPPYP00000005918	ENSPPYP00000006587	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.	Valosin containing protein lysine methyltransferase.	0.587
EEF1AKMT2	ATPSCKMT	ENSPPYP00000003202	ENSPPYP00000017137	EEF1AKMT2 isoform 2.	FAM173B isoform 2.	0.526
EEF1AKMT2	CSKMT	ENSPPYP00000003202	ENSPPYP00000003646	EEF1AKMT2 isoform 2.	Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial; Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria. Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methly group per binding event.	0.485
EEF1AKMT2	EEF1AKMT1	ENSPPYP00000003202	ENSPPYP00000005918	EEF1AKMT2 isoform 2.	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.	0.695
EEF1AKMT2	EEF1AKNMT	ENSPPYP00000003202	ENSPPYP00000000590	EEF1AKMT2 isoform 2.	METTL13 isoform 4.	0.605
EEF1AKMT2	METTL18	ENSPPYP00000003202	ENSPPYP00000000611	EEF1AKMT2 isoform 2.	Methyltransferase like 18.	0.542
EEF1AKMT2	VCPKMT	ENSPPYP00000003202	ENSPPYP00000006587	EEF1AKMT2 isoform 2.	Valosin containing protein lysine methyltransferase.	0.578