GNG2 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	GIPR	ENSPPYP00000015070	ENSPPYP00000011327	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family.	0.592
ADCY5	GNAO1	ENSPPYP00000015070	ENSPPYP00000008317	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAO1 isoform 1.	0.954
ADCY5	GNAS	ENSPPYP00000015070	ENSPPYP00000012485	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS isoform 2.	0.986
ADCY5	GNB1	ENSPPYP00000015070	ENSPPYP00000002307	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.983
ADCY5	GNG2	ENSPPYP00000015070	ENSPPYP00000006605	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).	0.918
ADCYAP1R1	GNAS	ENSPPYP00000019802	ENSPPYP00000012485	ADCYAP1R1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	GNAS isoform 2.	0.928
ADCYAP1R1	GNB1	ENSPPYP00000019802	ENSPPYP00000002307	ADCYAP1R1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.932
ADCYAP1R1	GNG2	ENSPPYP00000019802	ENSPPYP00000006605	ADCYAP1R1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).	0.912
GABBR2	GNAO1	ENSPPYP00000021779	ENSPPYP00000008317	GABBR2 isoform 2.	GNAO1 isoform 1.	0.937
GABBR2	GNB1	ENSPPYP00000021779	ENSPPYP00000002307	GABBR2 isoform 2.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.960
GABBR2	GNG2	ENSPPYP00000021779	ENSPPYP00000006605	GABBR2 isoform 2.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).	0.923
GABBR2	KCNJ6	ENSPPYP00000021779	ENSPPYP00000012893	GABBR2 isoform 2.	G protein-activated inward rectifier potassium channel 2; This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G- protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due t [...]	0.952
GIPR	ADCY5	ENSPPYP00000011327	ENSPPYP00000015070	GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.592
GIPR	GNAS	ENSPPYP00000011327	ENSPPYP00000012485	GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family.	GNAS isoform 2.	0.942
GIPR	GNB1	ENSPPYP00000011327	ENSPPYP00000002307	GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.993
GIPR	GNG2	ENSPPYP00000011327	ENSPPYP00000006605	GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).	0.981
GLP1R	GNAS	ENSPPYP00000018535	ENSPPYP00000012485	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	GNAS isoform 2.	0.954
GLP1R	GNB1	ENSPPYP00000018535	ENSPPYP00000002307	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.979
GLP1R	GNG2	ENSPPYP00000018535	ENSPPYP00000006605	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).	0.912
GNAO1	ADCY5	ENSPPYP00000008317	ENSPPYP00000015070	GNAO1 isoform 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.954