| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALPG | ALPL | ENSPPYP00000014842 | ENSPPYP00000002041 | Alkaline phosphatase. | Alkaline phosphatase. | 0.912 |
| ALPG | GCH1 | ENSPPYP00000014842 | ENSPPYP00000006627 | Alkaline phosphatase. | GTP cyclohydrolase 1. | 0.900 |
| ALPG | PTS | ENSPPYP00000014842 | ENSPPYP00000004445 | Alkaline phosphatase. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity). | 0.900 |
| ALPL | ALPG | ENSPPYP00000002041 | ENSPPYP00000014842 | Alkaline phosphatase. | Alkaline phosphatase. | 0.912 |
| ALPL | GCH1 | ENSPPYP00000002041 | ENSPPYP00000006627 | Alkaline phosphatase. | GTP cyclohydrolase 1. | 0.900 |
| ALPL | PTS | ENSPPYP00000002041 | ENSPPYP00000004445 | Alkaline phosphatase. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity). | 0.900 |
| GCH1 | ALPG | ENSPPYP00000006627 | ENSPPYP00000014842 | GTP cyclohydrolase 1. | Alkaline phosphatase. | 0.900 |
| GCH1 | ALPL | ENSPPYP00000006627 | ENSPPYP00000002041 | GTP cyclohydrolase 1. | Alkaline phosphatase. | 0.900 |
| GCH1 | GCHFR | ENSPPYP00000006627 | ENSPPYP00000007200 | GTP cyclohydrolase 1. | GTP cyclohydrolase I feedback regulator. | 0.986 |
| GCH1 | GUCY2C | ENSPPYP00000006627 | ENSPPYP00000004933 | GTP cyclohydrolase 1. | Guanylate cyclase. | 0.854 |
| GCH1 | MOCS1 | ENSPPYP00000006627 | ENSPPYP00000018545 | GTP cyclohydrolase 1. | MOCS1 isoform 3. | 0.930 |
| GCH1 | NME2 | ENSPPYP00000006627 | ENSPPYP00000005726 | GTP cyclohydrolase 1. | Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...] | 0.815 |
| GCH1 | NME3 | ENSPPYP00000006627 | ENSPPYP00000007881 | GTP cyclohydrolase 1. | Nucleoside diphosphate kinase. | 0.815 |
| GCH1 | NME4 | ENSPPYP00000006627 | ENSPPYP00000007822 | GTP cyclohydrolase 1. | Nucleoside diphosphate kinase. | 0.814 |
| GCH1 | NUDT2 | ENSPPYP00000006627 | ENSPPYP00000021430 | GTP cyclohydrolase 1. | Nudix hydrolase 2. | 0.865 |
| GCH1 | PTS | ENSPPYP00000006627 | ENSPPYP00000004445 | GTP cyclohydrolase 1. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity). | 0.991 |
| GCHFR | GCH1 | ENSPPYP00000007200 | ENSPPYP00000006627 | GTP cyclohydrolase I feedback regulator. | GTP cyclohydrolase 1. | 0.986 |
| GCHFR | PTS | ENSPPYP00000007200 | ENSPPYP00000004445 | GTP cyclohydrolase I feedback regulator. | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity). | 0.877 |
| GUCY2C | GCH1 | ENSPPYP00000004933 | ENSPPYP00000006627 | Guanylate cyclase. | GTP cyclohydrolase 1. | 0.854 |
| GUCY2C | MOCS1 | ENSPPYP00000004933 | ENSPPYP00000018545 | Guanylate cyclase. | MOCS1 isoform 3. | 0.851 |
