TBPL2 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDP1	BRF1	ENSPPYP00000017362	ENSPPYP00000007048	BDP1 isoform 3.	BRF1 isoform 7.	0.995
BDP1	TBP	ENSPPYP00000017362	ENSPPYP00000019257	BDP1 isoform 3.	TBP isoform 3.	0.981
BDP1	TBPL2	ENSPPYP00000017362	ENSPPYP00000006636	BDP1 isoform 3.	TATA-box binding protein like 2.	0.940
BRF1	BDP1	ENSPPYP00000007048	ENSPPYP00000017362	BRF1 isoform 7.	BDP1 isoform 3.	0.995
BRF1	GTF2B	ENSPPYP00000007048	ENSPPYP00000001365	BRF1 isoform 7.	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	0.737
BRF1	TBP	ENSPPYP00000007048	ENSPPYP00000019257	BRF1 isoform 7.	TBP isoform 3.	0.986
BRF1	TBPL2	ENSPPYP00000007048	ENSPPYP00000006636	BRF1 isoform 7.	TATA-box binding protein like 2.	0.951
GTF2B	BRF1	ENSPPYP00000001365	ENSPPYP00000007048	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	BRF1 isoform 7.	0.737
GTF2B	SP1	ENSPPYP00000001365	ENSPPYP00000005222	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	Sp1 transcription factor.	0.599
GTF2B	TAF12	ENSPPYP00000001365	ENSPPYP00000001889	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	TAF12 isoform 2.	0.955
GTF2B	TAF3	ENSPPYP00000001365	ENSPPYP00000002407	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	TAF3 isoform 1.	0.887
GTF2B	TAF6	ENSPPYP00000001365	ENSPPYP00000019499	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	TAF6 isoform 4.	0.941
GTF2B	TAF8	ENSPPYP00000001365	ENSPPYP00000018575	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	TATA-box binding protein associated factor 8.	0.917
GTF2B	TBP	ENSPPYP00000001365	ENSPPYP00000019257	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	TBP isoform 3.	0.999
GTF2B	TBPL2	ENSPPYP00000001365	ENSPPYP00000006636	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	TATA-box binding protein like 2.	0.995
NFYA	SP1	ENSPPYP00000018553	ENSPPYP00000005222	Nuclear transcription factor Y subunit alpha.	Sp1 transcription factor.	0.856
NFYA	TAF8	ENSPPYP00000018553	ENSPPYP00000018575	Nuclear transcription factor Y subunit alpha.	TATA-box binding protein associated factor 8.	0.492
NFYA	TBP	ENSPPYP00000018553	ENSPPYP00000019257	Nuclear transcription factor Y subunit alpha.	TBP isoform 3.	0.944
NFYA	TBPL2	ENSPPYP00000018553	ENSPPYP00000006636	Nuclear transcription factor Y subunit alpha.	TATA-box binding protein like 2.	0.941
SP1	GTF2B	ENSPPYP00000005222	ENSPPYP00000001365	Sp1 transcription factor.	Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...]	0.599