STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOJRas homolog family member J. (214 aa)    
Predicted Functional Partners:
ITSN2
ITSN2 isoform 3.
    
 0.979
ITSN1
ITSN1 isoform 4.
    
 0.916
PARD6B
Par-6 family cell polarity regulator beta.
    
 0.911
PRKCI
Protein kinase C iota type; Calcium- and diacylglycerol-independent serine/ threonine- protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis. In cultured neurons, prevents amyloid beta protein-induced apoptosis by interrupting cell death process [...]
   
 0.820
DOCK8
DOCK8 isoform 2; Belongs to the DOCK family.
   
 0.819
DOCK11
DOCK11 isoform 1; Belongs to the DOCK family.
   
 0.715
MYO9A
MYO9A isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.714
MYO9B
MYO9B isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.714
PAK1
Non-specific serine/threonine protein kinase.
   
 0.685
PAK2
Non-specific serine/threonine protein kinase.
   
 0.667
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.