ESR2 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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Experiments

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[Homology]

Score

ESR2

ESR2 isoform 12. (531 aa)

Predicted Functional Partners:

ESR1

0.999

NCOA3

0.996

NCOA1

0.993

SRC

0.987

NCOA2

0.986

MED1

0.984

SP1

0.982

ENSPPYP00000024510

0.970

NCOR1

0.969

FOS

0.962

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000024510	ESR1	ENSPPYP00000024510	ENSPPYP00000019159	annotation not available	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.977
ENSPPYP00000024510	ESR2	ENSPPYP00000024510	ENSPPYP00000006703	annotation not available	ESR2 isoform 12.	0.970
ENSPPYP00000024510	MED1	ENSPPYP00000024510	ENSPPYP00000009539	annotation not available	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	0.722
ENSPPYP00000024510	NCOA1	ENSPPYP00000024510	ENSPPYP00000014068	annotation not available	Nuclear receptor coactivator.	0.824
ENSPPYP00000024510	NCOA2	ENSPPYP00000024510	ENSPPYP00000024008	annotation not available	Nuclear receptor coactivator.	0.921
ENSPPYP00000024510	NCOA3	ENSPPYP00000024510	ENSPPYP00000012407	annotation not available	Nuclear receptor coactivator.	0.881
ENSPPYP00000024510	NCOR1	ENSPPYP00000024510	ENSPPYP00000009011	annotation not available	NCOR1 isoform 1.	0.641
ENSPPYP00000024510	SRC	ENSPPYP00000024510	ENSPPYP00000012270	annotation not available	Tyrosine-protein kinase.	0.434
ESR1	ENSPPYP00000024510	ENSPPYP00000019159	ENSPPYP00000024510	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	annotation not available	0.977
ESR1	ESR2	ENSPPYP00000019159	ENSPPYP00000006703	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	ESR2 isoform 12.	0.999
ESR1	FOS	ENSPPYP00000019159	ENSPPYP00000006826	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.989
ESR1	MED1	ENSPPYP00000019159	ENSPPYP00000009539	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	0.997
ESR1	NCOA1	ENSPPYP00000019159	ENSPPYP00000014068	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.995
ESR1	NCOA2	ENSPPYP00000019159	ENSPPYP00000024008	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.998
ESR1	NCOA3	ENSPPYP00000019159	ENSPPYP00000012407	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.999
ESR1	NCOR1	ENSPPYP00000019159	ENSPPYP00000009011	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	NCOR1 isoform 1.	0.992
ESR1	SP1	ENSPPYP00000019159	ENSPPYP00000005222	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Sp1 transcription factor.	0.998
ESR1	SRC	ENSPPYP00000019159	ENSPPYP00000012270	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Tyrosine-protein kinase.	0.999
ESR2	ENSPPYP00000024510	ENSPPYP00000006703	ENSPPYP00000024510	ESR2 isoform 12.	annotation not available	0.970
ESR2	ESR1	ENSPPYP00000006703	ENSPPYP00000019159	ESR2 isoform 12.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.999