SPATA7 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIPL1	IMPDH1	ENSPPYP00000008865	ENSPPYP00000020165	Aryl hydrocarbon receptor interacting protein like 1.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.568
AIPL1	LRAT	ENSPPYP00000008865	ENSPPYP00000016922	Aryl hydrocarbon receptor interacting protein like 1.	LRAT isoform 2.	0.633
AIPL1	RD3	ENSPPYP00000008865	ENSPPYP00000000252	Aryl hydrocarbon receptor interacting protein like 1.	RD3 isoform 1.	0.615
AIPL1	RDH12	ENSPPYP00000008865	ENSPPYP00000006738	Aryl hydrocarbon receptor interacting protein like 1.	Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.645
AIPL1	RPGRIP1	ENSPPYP00000008865	ENSPPYP00000006362	Aryl hydrocarbon receptor interacting protein like 1.	RPGRIP1 isoform 8.	0.690
AIPL1	SPATA7	ENSPPYP00000008865	ENSPPYP00000006877	Aryl hydrocarbon receptor interacting protein like 1.	Spermatogenesis associated 7.	0.678
ENSPPYP00000010578	SPATA7	ENSPPYP00000010578	ENSPPYP00000006877	annotation not available	Spermatogenesis associated 7.	0.606
IMPDH1	AIPL1	ENSPPYP00000020165	ENSPPYP00000008865	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	Aryl hydrocarbon receptor interacting protein like 1.	0.568
IMPDH1	LRAT	ENSPPYP00000020165	ENSPPYP00000016922	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	LRAT isoform 2.	0.524
IMPDH1	RD3	ENSPPYP00000020165	ENSPPYP00000000252	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	RD3 isoform 1.	0.568
IMPDH1	RDH12	ENSPPYP00000020165	ENSPPYP00000006738	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.642
IMPDH1	RPGRIP1	ENSPPYP00000020165	ENSPPYP00000006362	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	RPGRIP1 isoform 8.	0.500
IMPDH1	SPATA7	ENSPPYP00000020165	ENSPPYP00000006877	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	Spermatogenesis associated 7.	0.610
LRAT	AIPL1	ENSPPYP00000016922	ENSPPYP00000008865	LRAT isoform 2.	Aryl hydrocarbon receptor interacting protein like 1.	0.633
LRAT	IMPDH1	ENSPPYP00000016922	ENSPPYP00000020165	LRAT isoform 2.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.524
LRAT	RD3	ENSPPYP00000016922	ENSPPYP00000000252	LRAT isoform 2.	RD3 isoform 1.	0.569
LRAT	RDH12	ENSPPYP00000016922	ENSPPYP00000006738	LRAT isoform 2.	Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.961
LRAT	RPGRIP1	ENSPPYP00000016922	ENSPPYP00000006362	LRAT isoform 2.	RPGRIP1 isoform 8.	0.546
LRAT	SPATA7	ENSPPYP00000016922	ENSPPYP00000006877	LRAT isoform 2.	Spermatogenesis associated 7.	0.655
RD3	AIPL1	ENSPPYP00000000252	ENSPPYP00000008865	RD3 isoform 1.	Aryl hydrocarbon receptor interacting protein like 1.	0.615