STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPATA7Spermatogenesis associated 7. (599 aa)    
Predicted Functional Partners:
RPGRIP1
RPGRIP1 isoform 8.
   
 
 0.714
AIPL1
Aryl hydrocarbon receptor interacting protein like 1.
      
 0.687
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.686
LRAT
LRAT isoform 2.
      
 0.684
RD3
RD3 isoform 1.
      
 0.682
RPE65
Retinoid isomerohydrolase RPE65.
   
  
 0.680
TULP1
Tubby-like protein; Belongs to the TUB family.
      
 0.675
IMPDH1
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
      
 0.675
CR201_G0010354
RPGR isoform 10.
   
 
 0.636
CEP290
CEP290 isoform 4.
      
 0.632
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.