ASB2 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB17	ASB2	ENSPPYP00000001428	ENSPPYP00000006928	ASB17 isoform 1.	ASB2 isoform 6.	0.731
ASB2	ASB17	ENSPPYP00000006928	ENSPPYP00000001428	ASB2 isoform 6.	ASB17 isoform 1.	0.731
ASB2	CUL5	ENSPPYP00000006928	ENSPPYP00000004398	ASB2 isoform 6.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.893
ASB2	ELOB	ENSPPYP00000006928	ENSPPYP00000007934	ASB2 isoform 6.	ELOB isoform 1.	0.737
ASB2	ELOC	ENSPPYP00000006928	ENSPPYP00000020952	ASB2 isoform 6.	ELOC isoform 10; Belongs to the SKP1 family.	0.781
ASB2	ENSPPYP00000004644	ENSPPYP00000006928	ENSPPYP00000004644	ASB2 isoform 6.	annotation not available	0.737
ASB2	ENSPPYP00000023677	ENSPPYP00000006928	ENSPPYP00000023677	ASB2 isoform 6.	annotation not available	0.781
ASB2	FLNA	ENSPPYP00000006928	ENSPPYP00000023360	ASB2 isoform 6.	FLNA isoform 7.	0.887
ASB2	FLNB	ENSPPYP00000006928	ENSPPYP00000015399	ASB2 isoform 6.	FLNB isoform 3.	0.834
ASB2	RNF7	ENSPPYP00000006928	ENSPPYP00000015846	ASB2 isoform 6.	Ring finger protein 7.	0.790
ASB2	UBC	ENSPPYP00000006928	ENSPPYP00000005811	ASB2 isoform 6.	UBC isoform 2.	0.764
CUL5	ASB2	ENSPPYP00000004398	ENSPPYP00000006928	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	ASB2 isoform 6.	0.893
CUL5	ELOB	ENSPPYP00000004398	ENSPPYP00000007934	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	ELOB isoform 1.	0.996
CUL5	ELOC	ENSPPYP00000004398	ENSPPYP00000020952	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	ELOC isoform 10; Belongs to the SKP1 family.	0.997
CUL5	ENSPPYP00000004644	ENSPPYP00000004398	ENSPPYP00000004644	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	annotation not available	0.992
CUL5	ENSPPYP00000023677	ENSPPYP00000004398	ENSPPYP00000023677	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	annotation not available	0.973
CUL5	RNF7	ENSPPYP00000004398	ENSPPYP00000015846	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Ring finger protein 7.	0.998
CUL5	UBC	ENSPPYP00000004398	ENSPPYP00000005811	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	UBC isoform 2.	0.839
ELOB	ASB2	ENSPPYP00000007934	ENSPPYP00000006928	ELOB isoform 1.	ASB2 isoform 6.	0.737
ELOB	CUL5	ENSPPYP00000007934	ENSPPYP00000004398	ELOB isoform 1.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.996