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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (413 aa)    
Predicted Functional Partners:
PDPK1
PDPK1 isoform 1.
  
0.980
CHUK
CHUK isoform 1.
   
0.979
CDC42
Cell division cycle 42.
   
 0.975
RICTOR
RICTOR isoform 1.
    
 0.973
FOXO1
FOXO1 isoform 1.
    
 0.969
BAD
BCL2 associated agonist of cell death.
    
 0.967
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 0.964
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.962
GSK3A
Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.
    
0.959
APPL1
APPL1 isoform 1.
    
 
 0.940
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.